Obesity

Canagliflozin or acarbose versus placebo to ameliorate post‐bariatric hypoglycaemia – The HypoBar I randomized clinical trial protocol

Diabet MedPublished Randomised controlled trial protocol

Study context

Population
Subjects with post-bariatric hypoglycaemia (PBH), mostly after RYGB
Planned comparison
Canagliflozin vs acarbose vs placebo
Methodological detailsdouble-blinded, crossover, Outcomes: effectiveness in reducing PBH risk, safety, ambulatory glucose profile and entero-endocrine responses during a 4-week intervention period
  • Double-blinded
  • Crossover
  • Outcomes: effectiveness in reducing PBH risk, safety, ambulatory glucose profile and entero-endocrine responses during a 4-week intervention period

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Canagliflozin or acarbose versus placebo to ameliorate post‐bariatric hypoglycaemia – The HypoBar I randomized clinical trial protocol. Diabet Med. Published 29 March 2024. doi:10.1111/dme.15320

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