Diabetes technology

Cambridge hybrid closed‐loop use in very young children with type 1 diabetes: Parental expectancies during long‐term home use

Diabet MedPublished Secondary analysis of a multinational randomised crossover trial with extension phase

Authors' conclusion

Prolonged HCL use supports sustained glycaemic benefits while parental positive expectancies regarding AID increase over time.

Study context

Population
Parents of young children aged 1–7 with T1D using CamAPS FX hybrid closed-loop (HCL)parents of children
Participants
64 parents
Comparison
Parental expectancies and HbA1c at baseline vs HCL clinical trial phase vs after 18-month home-use extension
Primary endpoint
Parental expectancies regarding automated insulin delivery (AID) (INSPIRE questionnaire)
Methodological details18-month HCL extension phase, linear mixed models
  • 18-month HCL extension phase
  • Linear mixed models

Primary result

As reported in the abstract

Parental expectancies (INSPIRE)

d

0.05

P = 0.629

Clinical trial · did not change

d

1.14

P < 0.001

18-month extension · increased markedly

Baseline

44.78

± 34.70

Clinical trial

42.10

± 38.11

18-month extension

89.83

± 9.35

Further findings

HbA1c — Clinical trial vs Baseline

P < 0.001

% Baseline 7.3% · Clinical trial 6.8% · 18-month extension 6.8%

OutcomeP value
HbA1c18-month extension vs Baseline · benefits sustainedP = 0.45

Original publication

Cambridge hybrid closed‐loop use in very young children with type 1 diabetes: Parental expectancies during long‐term home use. Diabet Med. Published 1 July 2026. doi:10.1111/dme.70408

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