Bone mineral density and lipid profiles in older adults: a nationwide cross-sectional study
Authors' conclusion
Serum triglycerides showed a significant inverse association with BMD, and the relationship is thought to correlate with vitamin D status among older adults.
Study context
- Population
- Men older than 50 years and postmenopausal women in Korean National Health and Nutrition Examination Survey (KNHANES) 2008–2011; excluded liver cirrhosis, thyroid disease, renal dysfunction, or treatment for hyperlipidemia or osteoporosisanalyzed
- Participants
- 4,323 participants
- Exposure
- Men vs Women
- Menn = 2,286
- Womenn = 2,037
- Outcome
- Relationship between lipid profiles and BMD
Methodological detailsnationwide, KNHANES 2008-2011, linear model adjusted for age and BMI
- Nationwide
- KNHANES 2008-2011
- Linear model adjusted for age and BMI
Main finding
As reported in the abstract
Association of lipid profiles with BMD (adjusted for age and BMI)
- Triglycerides negatively associated with whole-body bone mineral density (BMD) in both men and women
- p < 0.05
Observational data: associations, not effects.
Further findings
Prevalence of osteoporosis
| Outcome | aOR (95% CI) | |
|---|---|---|
| Osteoporosis per logarithmic triglyceride level, women older than 65 years (subgroup) | 2.50 (1.13–5.51) | |
| 0.20.5125Adjusted odds ratio (log scale) |
Characteristics of osteopenia and osteoporosis vs normal
- Osteopenia and osteoporosis groups generally older and tended to have lower BMI than normal group
- P for trend < 0.001
Original publication
Bone mineral density and lipid profiles in older adults: a nationwide cross-sectional study. Osteoporos Int. Published 18 October 2022. doi:10.
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