Diabetes complications

BedBiopsy: Diagnostic performance of bedside ultrasound-guided bone biopsies for the management of diabetic foot infection

Diabetes MetabPublished Retrospective cohort study

Authors' conclusion

In diabetic patients with suspected foot osteitis not requiring surgery, bedside ultrasound-guided bone biopsies may constitute a promising alternative to surgical biopsies. This intervention provided excellent tolerance and microbiological documentation, short lead-times, and more favorable wound prognosis.

Study context

Population
Diabetic patients admitted for suspected foot osteitis not requiring surgery
Participants
29 vs 24
Exposure
Bedside US-guided vs surgical bone biopsies
  • Ultrasound-guidedn = 29
  • Surgicaln = 24reference
Outcome
Diagnostic performance: confirming or ruling out diabetic foot osteitis
Methodological detailsmonocentric, consecutive patients
  • Monocentric
  • Consecutive patients

Main finding

As reported in the abstract

Diagnostic performance (confirm or rule out suspected osteitis)
GroupValueConfirmationsInvalidations
Ultrasound-guided28/29253
Surgical24/2424

Value

Ultrasound-guided28/29
Surgical24/24

Confirmations

Ultrasound-guided25
Surgical24

Invalidations

Ultrasound-guided3
Surgical— not stated in the abstract
  • Ultrasound-guided vs Surgical: P = 0.358 — similar

Observational data: associations, not effects.

Further findings

Time to perform biopsy · shorter with Ultrasound-guided

P < 0.001

Favorable wound evolution · 3 months

P = 0.005

Favorable wound evolution, excluding patients with new surgical procedure within 6 months

P = 0.055

Wound healing · 6 months

P = 0.790

Osteitis healing · 6 months

P = 0.071

Safety

No biopsy-related side effect or complication was observed for either intervention, even for patients on antiaggregation and/or anticoagulation therapy

Original publication

BedBiopsy: Diagnostic performance of bedside ultrasound-guided bone biopsies for the management of diabetic foot infection. Diabetes Metab. Published 3 March 2024. doi:10.1016/j.diabet.2024.101525

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