Baseline Urine Albumin-to-Creatinine Ratio is Associated With Decline of Estimated Glomerular Filtration Rate in Patients Newly Diagnosed With Type 2 Diabetes Mellitus: An Observational 5-year Cohort Study
Authors' conclusion
The prevalence of albuminuria is 18.8% in patients newly diagnosed with type 2 diabetes and the occurrence of albuminuria can predict steeper annual decline in kidney function.
Study context
- Population
- Patients aged ≥18 years newly diagnosed with T2D (January 2014–31 December 2017), outpatient clinic of a tertiary hospital in China
- Participants
- 604 patients
- Exposure
- Baseline albuminuria vs normoalbuminuria
- Outcome
- Progression of DKD estimated by eGFR slope
- Follow-up
- 5-year follow-up
Methodological detailssingle-centre, 5-year follow-up
- Single-centre
- 5-year follow-up
Main finding
As reported in the abstract
eGFR decline
Albuminuria
−2.6
mL/min/1.73 m² per year
Normoalbuminuria
−1.5
mL/min/1.73 m² per year
P = 0.01
Observational data: associations, not effects.
Further findings
Prevalence of albuminuria at diagnosis of T2D · baseline
- Albuminuria
- 18.8%
- Microalbuminuria
- 17.4%
- Macroalbuminuria
- 1.4%
Original publication
Baseline Urine Albumin-to-Creatinine Ratio is Associated With Decline of Estimated Glomerular Filtration Rate in Patients Newly Diagnosed With Type 2 Diabetes Mellitus: An Observational 5-year Cohort Study. Endocr Pract. Published 2 November 2023. doi:10.
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