Automated Insulin Delivery with Remote Real-Time Continuous Glucose Monitoring for Hospitalized Patients with Diabetes: A Multicenter, Single-Arm, Feasibility Trial
Authors' conclusion
The use of AID with a disposable tubeless patch-pump along with remote real-time CGM is feasible in the hospital setting.
Study context
- Population
- Hospitalized patients with insulin-requiring diabetes on non-ICU medical-surgical units16 analysed
- Participants
- 22 patients
- Outcome
- Proportion of time in automated mode and percent TIR (70-180 mg/dL) among participants with >48 h of CGM data
Methodological detailsmulticenter, pilot, 18 of 22 used the system for a total of 96 days (mean 5.3 ± 3.1 days per patient)
- Multicenter
- Pilot
- 18 of 22 used the system for a total of 96 days (mean 5.3 ± 3.1 days per patient)
Main finding
As reported in the abstract
Time in automated mode (18 system users), median (IQR 92%-98%)
95%
TIR 70-180 mg/dL (16 participants), mean ± SD
68% ± 16%
Further findings
Time <70 mg/dL and <54 mg/dL; sensor mean glucose
- Time <70 mg/dL
- 0.17% ± 0.3%
- Time <54 mg/dL
- 0.06% ± 0.2%
- Sensor mean glucose
- 167 ± 21 mg/dL
Patient satisfaction · study end
- All participants reported satisfaction with the system
Safety
Severe hypoglycaemia and DKA
- There were no DKA or severe hypoglycemic events
Hypoglycaemia (continuous glucose monitoring (CGM) time below range)
- Time <70 mg/dL
- 0.17% ± 0.3%
- Time <54 mg/dL
- 0.06% ± 0.2%
- 16 participants with >48 h of CGM data
Original publication
Automated Insulin Delivery with Remote Real-Time Continuous Glucose Monitoring for Hospitalized Patients with Diabetes: A Multicenter, Single-Arm, Feasibility Trial. Diabetes Technol Ther. Published 28 August 2023. doi:10.
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