The associations of maternal and paternal obesity with latent patterns of offspring BMI development between 7 and 17 years of age: pooled analyses of cohorts born in 1958 and 2001 in the United Kingdom
Authors' conclusion
The increase in obesity rates in the UK over more than 40 years has been partly driven by the growth of a sub-population demonstrating excess BMI gain during adolescence. Our results implicate both maternal and paternal BMI as correlates of this secular process.
Study context
- Population
- UK children with serial BMI data between 7 and 17 years of age; half born in 1958 and half in 200113,220 boys · 12,711 girls
- Comparison
- Both parents with overweight or obesity vs both parents with normal weight
- Outcome
- Latent classes of BMI development (5-class models per sex)
- Follow-up
- 7 to 17 years
Methodological detailsgrowth mixture models, sex-specific, 3-step BCH approach, covariate adjustment
- Growth mixture models
- Sex-specific
- 3-step BCH approach
- Covariate adjustment
Pooled result
As reported in the abstract
- "Normal weight increasing to overweight" class (boys and girls)
- 17% and 20%
- "Overweight increasing to obesity" class (boys and girls)
- 8% and 6%
- "Overweight decreasing to normal weight" class (boys and girls)
- 3% and 6%
- "Overweight increasing to obesity" class: 2001 birth cohort vs 1958 birth cohort
- More than 1-in-10 vs less than 1-in-30
- Mothers and fathers of "overweight increasing to obesity" class with overweight or obesity
- ≈75%
Further pooled results
| Outcome | Odds (CI) |
|---|---|
| Odds of "overweight increasing to obesity" class (vs largest normal weight class), girlsTimes higher | 13.11 (8.74–19.66) |
| Odds of "overweight increasing to obesity" class (vs largest normal weight class), boys | 9.01 (6.37–12.75) |
Maternal and paternal BMI and latent class membership
- Both maternal and paternal BMI associated with class membership, with negative departure from additivity (combined effect smaller than sum of individual effects)
Original publication
The associations of maternal and paternal obesity with latent patterns of offspring BMI development between 7 and 17 years of age: pooled analyses of cohorts born in 1958 and 2001 in the United Kingdom. Int J Obes (Lond). Published 10 November 2022. doi:10.
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