Association of weight loss with cardiovascular or all-cause mortality in patients with heart failure: A meta-analysis
Pooled result · All-cause mortalityResult — go to the resultPooled adjusted hazard ratio 1.75 95% CI 1.43–2.14Authors' conclusion
Weight loss is associated with an increased risk of cardiovascular and all-cause mortality in patients with HF. Assessing weight changes can provide prognostic information for patients with HF.
Study context
- Population
- Patients with heart failure (HF); PubMed and Embase searched up to May 7, 202312 articles
- Participants
- 26,164 patients13 studies
- Comparison
- Weight loss vs stable weight
- Outcome
- All-cause mortality
Pooled result
As reported in the abstract
Pooled adjusted hazard ratio
1.75
95% CI 1.43–2.14
Weight lossvs Stable weight
pooled adjusted HR 1.75 (95% CI 1.43–2.14)
Further pooled results
| Outcome | Estimate | |
|---|---|---|
| All-cause mortality, overweight/obese subgroup | HR 1.76 (95% CI 1.41–2.20) | |
| All-cause mortality, not overweight/obese subgroup | HR 1.90 (95% CI 1.14–3.14) | |
| CV mortalityWeight lossvs No weight loss | pooled adjusted HR 1.64 (95% CI 1.18–2.28) | |
| 0.20.5125Ratio (log scale) |
Original publication
Association of weight loss with cardiovascular or all-cause mortality in patients with heart failure: A meta-analysis. Int J Obes (Lond). Published 5 February 2024. doi:10. 1038/ s41366-024-01484-9
Composed by AI from the published abstract and checked against it. How Briefs are made →