Association of Longitudinal Activity Measures and Diabetes Risk: An Analysis From the National Institutes of Health All of Us Research Program
Main finding · Hazard of incident diabetesResult — go to the resultReduction in hazard 44% 95% CI 15%–63%Authors' conclusion
Greater time in any type of physical activity intensity was associated with lower risk of T2DM irrespective of age, sex, BMI, or sedentary time.
Study context
- Population
- All of Us Research Program participants with personal Fitbit accelerometer data; median age 51 years, 74% female, 89% White; 2010 to 202197 (2%) incident T2D cases
- Participants
- 5,677 participants
- Exposure
- Average daily step count of 10 700 vs 6000
- Outcome
- Incident T2D
- Follow-up
- Median 3.8 years
Methodological detailstime-varying Cox proportional hazards models with repeated measures of physical activity, commercial wearable device (Fitbit) data linked to electronic health records
- Time-varying Cox proportional hazards models with repeated measures of physical activity
- Commercial wearable device (Fitbit) data linked to electronic health records
Main finding
Hazard of incident diabetes
Reduction in hazard
44%
95% CI 15%–63%
P = 0.01
As reported in the abstract
Observational data: associations, not effects.
Further findings
Average duration of activity intensities (lightly, fairly, very active)
- Similar benefits seen comparing groups by average duration of various activity intensities
Effect modification by age, sex, body mass index (BMI) or sedentary time
- No evidence for effect modification by age, sex, BMI, or sedentary time
Original publication
Association of Longitudinal Activity Measures and Diabetes Risk: An Analysis From the National Institutes of Health All of Us Research Program. J Clin Endocrinol Metab. Published 2 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →