Association of Baseline Thyroid Stimulating Hormone With In-Hospital Outcomes in Patients With Atrial Fibrillation and Coronary Artery Diseases
Authors' conclusion
Higher baseline TSH presented a protective effect on in-hospital all-cause death and HF in patients with AF combined with CAD.
Study context
- Population
- Patients with atrial fibrillation (AF) and coronary artery disease (CAD)patients with AF
- Participants
- 19,725 patients
- Exposure
- Median and high vs low baseline thyroid stimulating hormone (TSH) tertile
- Outcome
- In-hospital outcomes: MACE, all-cause death or HF
- Follow-up
- In-hospital
Methodological detailstertiles of baseline TSH, logistic regression
- Tertiles of baseline TSH
- Logistic regression
Main finding
As reported in the abstract
In-hospital all-cause death
Each group vs Low-TSHOdds ratio (95% CI)P value
Median-TSH
0.277(0.078–0.991)
P = 0.048High-TSH
0.163(0.036–0.750)
P = 0.020Observational data: associations, not effects.
Further findings
In-hospital HF events
- High TSH showed a protective role for HF events
In-hospital HF events, subgroups
- Same results seen in females, age ≥75 and non-non-hypertension subgroups
Original publication
Association of Baseline Thyroid Stimulating Hormone With In-Hospital Outcomes in Patients With Atrial Fibrillation and Coronary Artery Diseases. Endocr Pract. Published 25 December 2024. doi:10.
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