Association between the triglyceride-glucose index and in-hospital major adverse cardiovascular events in patients with acute coronary syndrome: results from the Improving Care for Cardiovascular Disease in China (CCC)-Acute Coronary Syndrome project
Authors' conclusion
In patients with ACS, the TyG index was an independent predictor of in-hospital MACEs. Special vigilance should be exercised in females, elderly individuals, and patients with renal insufficiency.
Study context
- Population
- Hospitalised patients with acute coronary syndrome, CCC-ACS database, China
- Participants
- 101,113 patients
- Exposure
- TyG index quartiles 2, 3 and 4 vs quartile 1
- Outcome
- In-hospital MACE: all-cause mortality, cardiac arrest, MI and stroke
- Follow-up
- During hospitalization
Methodological detailsregistry-based (CCC-ACS database)
- Registry-based (CCC-ACS database)
Main finding
As reported in the abstract
In-hospital MACE
Hazard ratio (95% CI)P value
Q3vs Q1
1.253(1.121–1.400)
P < 0.001for trendQ4vs Q1
1.604(1.437–1.791)
P < 0.001for trendObservational data: associations, not effects.
Further findings
Components of in-hospital MACE (2759 events) · during hospitalization
- All-cause mortality
- 1554 (49.1%)
- Cardiac arrest
- 601 (21.8%)
- Myocardial infarction (MI)
- 251 (9.1%)
- Stroke
- 353 (12.8%)
Interactions of TyG index with subgroups
- Interactions between TyG index and age, sex, diabetes status, renal insufficiency status and previous PCI
- all p values for interactions < 0.05
Original publication
Association between the triglyceride-glucose index and in-hospital major adverse cardiovascular events in patients with acute coronary syndrome: results from the Improving Care for Cardiovascular Disease in China (CCC)-Acute Coronary Syndrome project. Cardiovasc Diabetol. Published 15 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →