Association between transitions in metabolic health and colorectal cancer across categories of body size phenotype: a prospective cohort study
Main finding · Colorectal cancer riskResult — go to the resultRisk increase 144% 95% CI 1.21–4.95Authors' conclusion
The MHO phenotype was a dynamic status over time, and converting to MU during follow-up and being initially MU were associated with having an increased risk of colorectal cancer, regardless of degree of obesity and body size phenotype.
Study context
- Population
- Community-based cohort; metabolic health and body size phenotype assessed at first examination 2006–2009 and at 2010/2011 examination
- Participants
- 70,987 participants
- Exposure
- Changes in metabolic health across body size phenotype categories
- Outcome
- Colorectal cancer
- Follow-up
- Median 11.04 years
Methodological detailscommunity-based
- Community-based
Main finding
Colorectal cancer risk
Risk increase
144%
95% CI 1.21–4.95
As reported in the abstract
Observational data: associations, not effects.
Further findings
Colorectal cancer incidence (overall) · median follow-up 11.04 years
- Participants who developed colorectal cancer
- 428 (0.60%)
Original publication
Association between transitions in metabolic health and colorectal cancer across categories of body size phenotype: a prospective cohort study. Obesity (Silver Spring). Published 22 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →