Association between the atherogenic index of plasma and adverse long-term prognosis in patients diagnosed with chronic coronary syndrome
Main finding · MACE incidenceResult — go to the resultAdjusted hazard ratio 7.892 95% CI 1.818–34.269Authors' conclusion
Our data indicate, for the first time, that AIP is independently associated with poor long-term prognosis in patients suffering from CCS. The optimal AIP cut-off value for predicting clinical MACE among CCS patients was 0.24.
Study context
- Population
- Patients with chronic coronary syndrome (CCS) who underwent coronary angiography; Atherogenic Index of Plasma (AIP) = log (TG/HDL-C)
- Participants
- 404 patients
- Exposure
- AIP quartiles Q4 vs Q1–Q3
- Outcome
- MACE
- Follow-up
- Median 35 months
Main finding
MACE incidence · median 35 months
Adjusted hazard ratio
7.892
95% CI 1.818–34.269
P = 0.006
By group
Q4vs Q1
aHR 7.892 (95% CI 1.818–34.269); P = 0.006
As reported in the abstract
- Major adverse cardiovascular events (MACE) events overall
- 88
- Q4 had the highest risk of MACE on Kaplan-Meier curves
- log-rank P = 0.014
Observational data: associations, not effects.
Further findings
Optimal AIP cut-off for predicting MACE (ROC)
- Optimal AIP cut-off
- 0.24
Original publication
Association between the atherogenic index of plasma and adverse long-term prognosis in patients diagnosed with chronic coronary syndrome. Cardiovasc Diabetol. Published 21 September 2023. doi:10. 1186/ s12933-023-01989-z
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