Association between stress hyperglycemia ratio (SHR) and long-term mortality in patients with ischemic stroke: a retrospective cohort study
Authors' conclusion
This study revealed that SHR is correlated with a heightened risk of six-year and in-hospital all-cause mortality in IS patients. A U-shaped nonlinear association is observed between SHR and six-year all-cause mortality. Therefore, SHR could potentially act as a significant predictor for adverse long-term outcomes in IS patients, thereby facilitating clinical decision-making and risk evaluation.
Study context
- Population
- Patients with ischemic stroke from an institutional stroke database, January 2016 to December 2023; mean age 69.3 ± 13.4 years, 64.8% male
- Participants
- 4,330 patients
- Exposure
- SHR tertiles and mortality
- Outcome
- All-cause mortality
- Follow-up
- Six years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
HR for all-cause mortality with SHR
1.605
95% CI 1.099–2.345P < 0.05
Observational data: associations, not effects.
Secondary outcomes
In-hospital all-cause mortality · hospitalization
- HR for in-hospital all-cause mortality with SHR
- 3.698 (95% CI 1.950-7.014; P < 0.05)
Six-year mortality in subgroups (non-diabetic, no AF, no endovascular treatment) · six years
- Both low and high SHR significantly elevated six-year mortality risk vs moderate SHR
Original publication
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