Association between stress hyperglycaemia and in‐hospital cardiac events after coronary artery bypass grafting in patients without diabetes: A retrospective observational study of 5450 patients
Main finding · MACEResult — go to the resultOdds ratio 2.32 95% CI 1.38–3.90Authors' conclusion
SH was significantly associated with an increased risk of MACEs, SSI and longer ICU stay after CABG in patients without diabetes. In addition, SH >10 mmol/L or that occurred in the ICU and lasted more than 48 h increased the risk of adverse outcomes.
Study context
- Population
- Patients without diabetes who underwent coronary artery bypass grafting (CABG)
- Participants
- 5,450 patients
- Exposure
- Stress hyperglycaemia vs no stress hyperglycaemia (SH)
- Outcome
- MACE: in-hospital mortality, acute MI, stroke and acute renal failure
- Follow-up
- In-hospital
Main finding
MACE
Odds ratio
2.32
95% CI 1.38–3.90
By group
SHvs No SH
OR 2.32 (95% CI 1.38–3.90)
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Surgical site infection (SSI)
P = 0.0003
| Outcome | Estimate | |
|---|---|---|
| Surgical site infection (SSI)Adjusted for confounders | OR 2.21 (95% CI 1.20–3.95) | |
| ICU LOSAdjusted for confounders | OR for longer ICU stay 12.27 (95% CI 9.41–16.92) | |
| 0.050.21520Ratio (log scale) |
ICU LOS
P < 0.0001
Postoperative complications by SH subgroup
- SH >10 mmol/L, or SH occurring in the intensive care unit (ICU) and lasting >48 h, had increased risks of postoperative complications
- P < 0.05
Original publication
Association between stress hyperglycaemia and in‐hospital cardiac events after coronary artery bypass grafting in patients without diabetes: A retrospective observational study of 5450 patients. Diabetes Obes Metab. Published 2 March 2023. doi:10.
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