Association between serum β‐oestradiol and health‐related quality of life in postmenopausal women with degenerative lumbar scoliosis
Authors' conclusion
In postmenopausal women, serum E2 levels in DLS patients are significantly reduced and low levels of E2 are associated with lower bone density and poorer quality of life.
Study context
- Population
- Postmenopausal women with degenerative lumbar scoliosis (DLS) and healthy postmenopausal controls
- Participants
- 168 vs 140
- Comparison
- Postmenopausal women with DLS vs healthy postmenopausal women
- DLSn = 168
- Controln = 140reference
- Outcome
- Serum E2 and lumbar spinal BMD
Main finding
As reported in the abstract
- Serum E2 reliable for predicting DLS by ROC
- p < .001
Observational data: associations, not effects.
Further findings
Correlations of serum E2
- Serum E2 negatively correlated with Cobb angle, VAS and Oswestry Disability Index (ODI)
- Serum E2 positively correlated with lumbar spinal bone mineral density (LSBMD) and SF-36 scores
Original publication
Association between serum β‐oestradiol and health‐related quality of life in postmenopausal women with degenerative lumbar scoliosis. Clin Endocrinol (Oxf). Published 12 June 2022. doi:10.
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