Association between personality, lifestyle behaviors, and cardiovascular diseases in type 2 diabetes mellitus: a population-based cohort study of UK Biobank data
Authors' conclusion
This study revealed which personality traits can influence CVD risk during T2DM and how patients might benefit from adopting healthy lifestyle behaviors in relation to personality.
Study context
- Population
- Patients with T2D identified from UK Biobank 2006–2010, followed until end of 2021
- Participants
- 8,794 patients
- Exposure
- Personality traits and healthy lifestyle behaviors vs cardiovascular disease (CVD) risk
- Outcome
- Composite of incident CVD:
- MI
- Ischemic stroke
- AF
- HF
- Follow-up
- Median 13.6 years
Methodological detailsUK Biobank
- UK Biobank
Main finding
As reported in the abstract
Composite CVD by diligence
Patients experiencing CVDs
2110
Diligence, adjusted HR (95% CI), composite CVD
0.93
0.89–0.97
Observational data: associations, not effects.
Secondary outcomes
Individual CVD outcomes by diligence
- Myocardial infarction (MI), adjusted HR
- 0.90 (0.82-1.00) (95% CI)
- Ischemic stroke, adjusted HR
- 0.83 (0.74-0.94) (95% CI)
- Atrial fibrillation (AF), adjusted HR
- 0.92 (0.85-0.98) (95% CI)
- Heart failure (HF), adjusted HR
- 0.84 (0.76-0.91) (95% CI)
Healthy lifestyle behaviors and composite CVD
- Healthy lifestyle behaviors significantly reduced the risk of composite CVDs in groups with high and low diligence
Structural equation model
- Diligence directly affected primary outcome risk or indirectly by modifying lifestyle behaviors
Original publication
Association between personality, lifestyle behaviors, and cardiovascular diseases in type 2 diabetes mellitus: a population-based cohort study of UK Biobank data. BMJ Open Diabetes Res Care. Published 10 September 2024. doi:10. 1136/ bmjdrc-2024-004244
Composed by AI from the published abstract and checked against it. How Briefs are made →