Type 2 & other diabetes

Association between personality, lifestyle behaviors, and cardiovascular diseases in type 2 diabetes mellitus: a population-based cohort study of UK Biobank data

BMJ Open Diabetes Res CarePublished Population-based cohort study

Authors' conclusion

This study revealed which personality traits can influence CVD risk during T2DM and how patients might benefit from adopting healthy lifestyle behaviors in relation to personality.

Study context

Population
Patients with T2D identified from UK Biobank 2006–2010, followed until end of 2021
Participants
8,794 patients
Exposure
Personality traits and healthy lifestyle behaviors vs cardiovascular disease (CVD) risk
Outcome
Composite of incident CVD:
  • MI
  • Ischemic stroke
  • AF
  • HF
Follow-up
Median 13.6 years
Methodological detailsUK Biobank
  • UK Biobank

Main finding

As reported in the abstract

Composite CVD by diligence

Patients experiencing CVDs

2110

Diligence, adjusted HR (95% CI), composite CVD

0.93

0.89–0.97

Observational data: associations, not effects.

Secondary outcomes

Individual CVD outcomes by diligence

Myocardial infarction (MI), adjusted HR
0.90 (0.82-1.00) (95% CI)
Ischemic stroke, adjusted HR
0.83 (0.74-0.94) (95% CI)
Atrial fibrillation (AF), adjusted HR
0.92 (0.85-0.98) (95% CI)
Heart failure (HF), adjusted HR
0.84 (0.76-0.91) (95% CI)

Healthy lifestyle behaviors and composite CVD

Healthy lifestyle behaviors significantly reduced the risk of composite CVDs in groups with high and low diligence

Structural equation model

Diligence directly affected primary outcome risk or indirectly by modifying lifestyle behaviors

Original publication

Association between personality, lifestyle behaviors, and cardiovascular diseases in type 2 diabetes mellitus: a population-based cohort study of UK Biobank data. BMJ Open Diabetes Res Care. Published 10 September 2024. doi:10.1136/bmjdrc-2024-004244

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