Association between insulin resistance–related indices and the risk of recurrence after catheter ablation in patients with nonvalvular atrial fibrillation
Authors' conclusion
Among the six IR surrogate indices, eGDR, CTI, TyG-BMI, and METS-IR were associated with AF recurrence after catheter ablation. eGDR showed the most favorable overall predictive performance.
Study context
- Population
- Patients with nonvalvular atrial fibrillation (AF) undergoing first-time catheter ablation, January 2022–March 2025
- Participants
- 590 patients
- Exposure
- Six insulin resistance (IR) surrogate indices and AF recurrence after catheter ablation
- Outcome
- AF recurrence
- Follow-up
- Within 1 year
Methodological detailstwo-centre
- Two-centre
Main finding
As reported in the abstract
1-year follow-up
Recurrence
167 patients
28.31%
Observational data: associations, not effects.
Further findings
Predictive performance
- Estimated glucose disposal rate (eGDR) showed the most favorable overall performance; CTI, triglyceride-glucose-body mass index (TyG-BMI) and metabolic score for insulin resistance (METS-IR) also provided incremental predictive value; TyG and TG/HDL-C relatively limited incremental value
Subgroup analyses
- Generally consistent results after false discovery rate correction
Original publication
Association between insulin resistance–related indices and the risk of recurrence after catheter ablation in patients with nonvalvular atrial fibrillation. Cardiovasc Diabetol. Published 25 July 2026. doi:10.
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