The association between the duration and degree of adiposity and appetitive trait trajectory profiles from childhood into early adolescence – results from the Generation XXI cohort
Authors' conclusion
Children with the highest cumulative adiposity between 4 and 13 y were more likely to present an 'avid appetite' during childhood. Additionally, having excessive weight at age 7 may indicate a higher appetite in subsequent years.
Study context
- Population
- Children of the Generation XXI birth cohort (Porto, Portugal) with weight and height measured at 4, 7, 10 and 13 y; appetitive traits by Children's Eating Behaviour Questionnaire at 7, 10 and 13 yfinal sample
- Participants
- 3,339 children
- Exposure
- Cumulative adiposity and appetitive trait trajectory profiles
- Outcome
- Association of body mass index (BMI) area under the curve (BMIAUC, accumulated adiposity) with appetitive trait trajectory profiles
- Follow-up
- BMI 4–13 y; appetite 7–13 y
Methodological detailspopulation-based birth cohort, multinomial logistic regression
- Population-based birth cohort
- Multinomial logistic regression
Main finding
As reported in the abstract
Each group vs moderate appetiteOdds ratio (95% CI)
Avid appetiteper BMIAUC; positive association
1.47(1.40–1.55)
Smallest appetiteper BMIAUC; negative association
0.78(0.73–0.83)
- Median monthly exposure to BMI area under the curve (BMIAUC)
- 17.4 kg/m²
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Overweight/obesity at 7 y and 'avid appetite' profile · 7 yAvid appetitevs Moderate appetiteOverweight/obesity at 7 y | 2.13 (1.42–3.21) | |
| 0.20.5125Odds ratio (log scale) |
- Overweight/obesity at 7 y and 'avid appetite' profile — Overweight/obesity at 7 y increased odds of 'avid appetite' profile
- 113%
Original publication
The association between the duration and degree of adiposity and appetitive trait trajectory profiles from childhood into early adolescence – results from the Generation XXI cohort. Int J Obes (Lond). Published 7 April 2025. doi:10. 1038/ s41366-025-01765-x
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