Obesity

The association between the duration and degree of adiposity and appetitive trait trajectory profiles from childhood into early adolescence – results from the Generation XXI cohort

Int J Obes (Lond)Published Prospective birth cohort study

Authors' conclusion

Children with the highest cumulative adiposity between 4 and 13 y were more likely to present an 'avid appetite' during childhood. Additionally, having excessive weight at age 7 may indicate a higher appetite in subsequent years.

Study context

Population
Children of the Generation XXI birth cohort (Porto, Portugal) with weight and height measured at 4, 7, 10 and 13 y; appetitive traits by Children's Eating Behaviour Questionnaire at 7, 10 and 13 yfinal sample
Participants
3,339 children
Exposure
Cumulative adiposity and appetitive trait trajectory profiles
Outcome
Association of body mass index (BMI) area under the curve (BMIAUC, accumulated adiposity) with appetitive trait trajectory profiles
Follow-up
BMI 4–13 y; appetite 7–13 y
Methodological detailspopulation-based birth cohort, multinomial logistic regression
  • Population-based birth cohort
  • Multinomial logistic regression

Main finding

As reported in the abstract

Each group vs moderate appetiteOdds ratio (95% CI)
Avid appetiteper BMIAUC; positive association
1.47(1.40–1.55)
Smallest appetiteper BMIAUC; negative association
0.78(0.73–0.83)
Median monthly exposure to BMI area under the curve (BMIAUC)
17.4 kg/m²

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)
Overweight/obesity at 7 y and 'avid appetite' profile · 7 yAvid appetitevs Moderate appetiteOverweight/obesity at 7 y2.13 (1.42–3.21)
Overweight/obesity at 7 y and 'avid appetite' profile — Overweight/obesity at 7 y increased odds of 'avid appetite' profile
113%

Original publication

The association between the duration and degree of adiposity and appetitive trait trajectory profiles from childhood into early adolescence – results from the Generation XXI cohort. Int J Obes (Lond). Published 7 April 2025. doi:10.1038/s41366-025-01765-x

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