Association between accelerometer-measured irregular sleep duration and longitudinal changes in body mass index in older adults
Main finding · BMI change (kg/m²), standardized to 3-year intervalsResult — go to the resultHigher BMI change 0.24 kg/m² 95% CI 0.08–0.40Authors' conclusion
Since irregular sleep duration is common, trials of interventions targeting sleep irregularity might lead to new public health strategies that tackle obesity.
Study context
- Population
- UK Biobank participants (mean age 63 years) who wore accelerometers for a week in 2013–2015 and had two body mass index (BMI) measurements on average 2.5 years apart
- Participants
- 10,572 participants
- Exposure
- Sleep duration SD >60 min vs ≤30 min
- Outcome
- BMI change (kg/m²), standardized to 3-year intervals, and incident obesity
Methodological detailsaccelerometer-measured sleep, UK Biobank
- Accelerometer-measured sleep
- UK Biobank
Main finding
As reported in the abstract
BMI change (kg/m²), standardized to 3-year intervals
Higher BMI change
0.24 kg/m²
95% CI 0.08–0.40
p-nonlinearity <0.02
SD > 60 minvs ≤30 min
higher BMI change 0.24 kg/m² (95% CI 0.08–0.40); p-nonlinearity <0.02
Observational data: associations, not effects.
Further findings
| Outcome | Higher risk (95% CI) | P value |
|---|---|---|
| Incident obesityHigher with SD >60 min | 80% (1.28–2.52) | p-nonlinearity <0.02 |
- Incident obesity: adjusted for sociodemographic factors, shift work, and follow-up period
Effect modification
- Age, sex, baseline BMI and BMI polygenic risk score did not appear to modify the association
Original publication
Association between accelerometer-measured irregular sleep duration and longitudinal changes in body mass index in older adults. Int J Obes (Lond). Published 6 April 2025. doi:10.
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