Association between diabetes mellitus and primary restenosis following endovascular treatment: a comprehensive meta-analysis of randomized controlled trials
Pooled result · Primary restenosis after endovascular treatmentResult — go to the resultRelative risk 1.43 95% CI 1.25–1.62Authors' conclusion
This meta-analysis of all currently available RCTs showed that patients with DM are more prone to primary restenosis after endovascular treatment.
Study context
- Population
- Patients undergoing endovascular treatment (percutaneous transluminal angioplasty (PTA) or stenting) of coronary or femoral popliteal artery lesions; RCTs searched in PubMed/Medline, EMBASE and Cochrane Library, 01/1990 to 12/2022
- Participants
- 31,066 patients20 RCTs
- Comparison
- Diabetes mellitus (DM) vs no DM
- Outcome
- Restenosis: >50% stenosis at angiography, or TLR of the primary operation lesion
- Follow-up
- During the
Methodological detailsrandom effects models, Grading of Recommendations Assessment, Development and Evaluation (GRADE)
- Random effects models
- GRADE
Pooled result
Primary restenosis after endovascular treatment
Relative risk
1.43
95% CI 1.25–1.62
P = 0.001
DMvs Without DM
RR 1.43 (95% CI 1.25–1.62); P = 0.001
As reported in the abstract
Original publication
Association between diabetes mellitus and primary restenosis following endovascular treatment: a comprehensive meta-analysis of randomized controlled trials. Cardiovasc Diabetol. Published 22 April 2024. doi:10.
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