Lipids & metabolic liver disease
Association between diabetes and in‐hospital outcomes in patients with metabolic dysfunction‐associated steatotic liver disease hospitalized for cardiovascular disease: A nationwide database study
Main finding · In-hospital mortalityResult — go to the resultOdds ratio 1.99 95% CI 1.60–2.47Authors' conclusion
Diabetes was associated with higher in-hospital mortality and complication rates among patients with MASLD hospitalized for CVD. Stratification of MASLD by metabolic phenotype, particularly in the presence of diabetes, may help improve risk assessment and inform more personalized clinical management in this population.
Study context
- Population
- Patients with MASLD hospitalized for cardiovascular disease (CVD), Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination, April 2012 to March 2023; median age 66 years, 66.9% male
- Participants
- 10,614 patients
- Exposure
- Diabetes vs no diabetes
- Diabetesn = 4,550
- Outcome
- In-hospital mortality
Methodological detailsnationwide database
- Nationwide database
Main finding
As reported in the abstract
Odds ratio
1.99
95% CI 1.60–2.47
P < 0.001
By group
Diabetesvs Without diabetes
OR 1.99 (95% CI 1.60–2.47); P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Overall complications
P < 0.001
Cardiac events
P < 0.001
Original publication
Association between diabetes and in‐hospital outcomes in patients with metabolic dysfunction‐associated steatotic liver disease hospitalized for cardiovascular disease: A nationwide database study. Diabet Med. Published 15 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →