Association between atherosclerotic index of plasma and long-term aortic-related adverse events in type B aortic dissection patients undergoing thoracic endovascular aortic repair
Authors' conclusion
Our research indicates that AIP is independently associated with 1-year and 5-year ARAEs in patients with TBAD following TEVAR, providing a novel metabolic perspective for the prognostic evaluation of this population.
Study context
- Population
- Patients with type B aortic dissection (TBAD) undergoing thoracic endovascular aortic repair (TEVAR)
- Participants
- 1,335 patients
- Exposure
- High vs low atherosclerotic index of plasma (AIP)
- Outcome
- Aortic-related adverse events (ARAEs)
- Follow-up
- 1 and 5 years after TEVAR
Methodological detailsAIP tertiles
- AIP tertiles
Main finding
As reported in the abstract
ARAEs · 1 and 5 years
- High AIP associated with increased risk of aortic-related adverse events (ARAEs) on Cox regression
- all P < 0.001
Observational data: associations, not effects.
Further findings
All-cause mortality and MACCEs
- No statistically significant differences in all-cause mortality and MACCEs
- all P > 0.05
Subgroup: timing of operation and 1-year ARAEs
- Timing of operation showed significant interaction with 1-year ARAEs
- P for interaction = 0.008
Predictive accuracy of AIP for ARAEs (time-dependent ROC) · 5-year period
- AUC approaching 0.8 throughout the 5-year period
Original publication
Association between atherosclerotic index of plasma and long-term aortic-related adverse events in type B aortic dissection patients undergoing thoracic endovascular aortic repair. Cardiovasc Diabetol. Published 5 March 2026. doi:10.
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