Assessment of forearm muscles with ultrasound shear wave elastography in patients with acromegaly
Authors' conclusion
The patients with acromegaly have an increased muscle thickness but decreased muscle stiffness in the forearm muscles responsible for elbow flexion. Acromegaly can lead to a permanent deterioration of the muscular structure regardless of the disease activity.
Study context
- Population
- Patients with acromegaly and healthy controls similar in gender, age and body mass index (BMI)
- Participants
- 45 vs 45
- Exposure
- Acromegaly vs healthy controls
- Acromegalyn = 45
- Controln = 45reference
- Outcome
- Sonoelastographic features (shear wave elastography (SWE) thickness and stiffness) of forearm muscles (brachioradialis, biceps brachii)
Methodological detailssingle-center, multidisciplinary
- Single-center
- Multidisciplinary
Main finding
As reported in the abstract
- Acromegaly vs Control: P = 0.034
- Acromegaly vs Control: P = 0.046
- Acromegaly vs Control: P = 0.001
- Acromegaly vs Control: P = 0.001
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| hSMI (BIA)Higher with Acromegaly | P = 0.004 |
| Dominant hand grip strengthSimilar | P = 0.594 |
Muscle thickness and stiffness by disease activity (acromegaly)
- Disease activity caused no significant difference in muscle thickness and stiffness
- P > 0.05
Original publication
Assessment of forearm muscles with ultrasound shear wave elastography in patients with acromegaly. Pituitary. Published 30 October 2023. doi:10.
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