Diabetes complications

Assessment of arterial stiffness in patients with diabetic retinopathy: A systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis

Authors' conclusion

Diabetic participants with DR exhibit increased arterial stiffness compared to diabetic participants without DR.

Study context

Population
Diabetic participants with and without diabetic retinopathy (DR); Medline and Scopus searched
Comparison
DR vs diabetes mellitus (DM) without retinopathy
Outcome
Arterial stiffness parameters: brachial ankle PWV, carotid-femoral PWV and augmentation index

Pooled result

As reported in the abstract

Arterial stiffness
DR vs Without DREstimate (95% CI)P value
8 studies; I2 = 89 %
SMD (brachial ankle PWV) 0.59(0.40–0.79)
P < 0.00001
4 studies; I2 = 91 %
SMD (carotid-femoral PWV) 0.86(0.55–1.18)
P < 0.00001
4 studies; I2 = 0 %
SMD (augmentation index) 0.23(0.13–0.32)
P < 0.00001

Original publication

Assessment of arterial stiffness in patients with diabetic retinopathy: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 22 March 2025. doi:10.1016/j.diabres.2025.112123

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