Anthropometric and DXA-derived measures of body composition in relation to pre-diabetes among adults
Authors' conclusion
Pre-diabetes prevalence increased as adiposity measurements increased, with VAT mass demonstrating the highest AUC for pre-diabetes.
Study context
- Population
- Adults aged 18–65 years in the Kuwait Wellbeing Study; pre-diabetes defined as 5.7≤HbA1c%≤6.4585 males · 599 females
- Participants
- 1,184 adults
- Exposure
- Anthropometric and DXA-derived adiposity measures in relation to pre-diabetes
- Outcome
- Pre-diabetes prevalence (aPR) by adiposity measures (body mass index (BMI), WHR, total body fat (TBF), android fat, gynoid fat, android-to-gynoid ratio, VAT mass, Lunar iDXA)
Main finding
As reported in the abstract
Pre-diabetes prevalence by adiposity measure
Adjusted prevalence ratio (95% CI)
BMI obesevs BMI normal
1.59(1.19–2.12)
WHR Q4vs WHR Q1
1.25(0.96–1.61)
TBF Q4vs TBF Q1
1.58(1.20–2.07)
Android fat Q4vs Android fat Q1
1.67(1.27–2.20)
Gynoid fat Q4vs Gynoid fat Q1
1.48(1.16–1.89)
Android-to-gynoid fat ratio Q4vs Android-to-gynoid fat ratio Q1
1.70(1.27–2.28)
VAT mass Q4vs VAT mass Q1
2.05(1.49–2.82)
Observational data: associations, not effects.
Further findings
| Outcome | aPR (CI) | |
|---|---|---|
| Gynoid fat and pre-diabetes by sexGynoid fat Q4, malesvs Gynoid fat Q1, males | 1.71 (1.22–2.41) | |
| Gynoid fat and pre-diabetes by sexGynoid fat Q4, femalesvs Gynoid fat Q1, femalesNot associated | 1.27 (0.90–1.78) | |
| 0.512Adjusted prevalence ratio (log scale) |
AUC for pre-diabetes
- Visceral adipose tissue (VAT) (highest AUC)
- 0.680
- Android-to-gynoid fat ratio
- 0.647
- Android fat
- 0.646
Original publication
Anthropometric and DXA-derived measures of body composition in relation to pre-diabetes among adults. BMJ Open Diabetes Res Care. Published 3 October 2023. doi:10.
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