Annual trends in glycemic control and prescribing patterns in diabetic treatment according to age in Japanese patients with type 2 diabetes between 2012 and 2019 (JDDM 71)
Authors' conclusion
There were no obvious changes in glycemic control over time in the study period. The mean HbA1c level was higher in younger patients, which suggested that improvement is required. In older patients, there was a trend toward greater emphasis on management to avoid hypoglycemia. Different treatment strategies based on age showed different drug choices.
Study context
- Population
- Japanese patients with T2D (JDDM), 2012–2019per year
- Participants
- ≈40,000 patients
- Exposure
- Age groups over time
- Outcome
- Changes in glycemic control and diabetes treatment by age group
- Follow-up
- 2012–2019
Methodological detailsrepeated annual cross-sectional analyses, 2012–2019
- Repeated annual cross-sectional analyses, 2012–2019
Main finding
As reported in the abstract
Age ≤44 years: highest hemoglobinA1c (HbA1c), 2012
7.4 % ± 1.7 %
Age ≤44 years: highest HbA1c, 2019
7.4 % ± 1.5 %
Age ≤44 years, insulin-treated: HbA1c 2012
8.3 % ± 1.9 %
Age ≤44 years, insulin-treated: HbA1c 2019
8.4 % ± 1.8 %
Observational data: associations, not effects.
Further findings
Prescribing patterns · 2012–2019
- Biguanides and DPP-4i widely prescribed
- SU and insulin use decreasing, but higher share of prescriptions in older patients
- SGLT2i prescribed rapidly, especially in younger patients
Original publication
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