An Adaptive Behavioral Intervention for Weight Loss Management: A Randomized Clinical Trial
An erratum to this article was published (JAMA, 24 Mar 2026 ↗)
Primary result · Weight changeResult — go to the resultDifference in weight change −2.0 kg 90% CI −2.9 to −1.1Authors' conclusion
A wireless feedback system (Wi-Fi activity tracker and scale with smartphone app to provide daily feedback) was not noninferior to the same system with added coaching. Continued efforts are needed to identify strategies for weight loss management and to accurately select interventions for different individuals to achieve weight loss goals.
Study context
- Population
- Adults aged 18 to 60 years with BMI 27 to 45; mean (SD) age 40.5 (11.2) years, 76.3% women; US academic medical center, June 2017–March 2021342 analysed at 6 months
- Participants
- 400 adults
- Comparison
- Wireless feedback system (WFS) vs WFS plus coaching
- WFSn = 199
- WFS plus coachingn = 201reference
- Primary endpoint
- Between-group difference in weight change; noninferiority margin −2.5 kg
- Follow-up
- 6 months
Methodological detailsnoninferiority, rerandomization of nonresponders to step-up interventions, outcome assessors blinded, participants and staff unblinded, single US academic medical center
- Noninferiority
- Rerandomization of nonresponders to step-up interventions
- Outcome assessors blinded
- Participants and staff unblinded
- Single US academic medical center
Primary result
Weight change
Difference in weight change
−2.0 kg
90% CI −2.9 to −1.1
P < 0.001
Change by group
WFS
−2.8
95% CI −3.5–-2.0 · kg
WFS plus coaching
−4.8
95% CI −5.5–-4.1 · kg
As reported in the abstract
Secondary outcomes
Weight change at 3 and 12 months
- Weight change differences were comparable at 3 and 12 months
Weight change among nonresponders, modest vs vigorous step-up · 6 months
- Among nonresponders, weight change differences comparable, with no difference by step-up therapy
Original publication
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