Accuracy of Dexcom G6 Pro Continuous Glucose Monitor in the Intensive Care Setting: TIGHT Intensive Care Unit (ICU) G6 Study
Authors' conclusion
Accuracy of the Dexcom G6 Pro sensor in the ICU setting was worse than has previously been reported for this sensor, with sensor values tending to be biased high. However, this appears to be a function of the G6 Pro sensor and not the setting as similar results were obtained in a non-ICU setting. Results should not be generalized to the real-time G6 or other sensors.
Study context
- Population
- Adult ICU patients with known diabetes or stress hyperglycemia treated with insulin; mean age 62 ± 12 years; preexisting diabetes 73%, stress hyperglycemia 27%9,120 sensor-BG pairs analysed
- Participants
- 130 vs 60
- Exposure
- ICU vs Non-ICU
- ICUn = 130
- Non-ICUn = 60
- Outcome
- Accuracy of Dexcom G6 Pro continuous glucose monitoring (CGM) vs BG measurements from usual ICU care (paired sensor-BG)
Methodological detailsmulticenter
- Multicenter
Main finding
As reported in the abstract
Sensor accuracy in ICU (9120 sensor-BG pairs)
- Mean relative absolute difference (RAD)
- 23% (median 19%)
- Mean difference (sensor vs blood glucose (BG))
- +25 mg/dL (median 25 mg/dL)
- Within 15%/15 mg/dL of BG
- 41%
- Within 20%/20 mg/dL of BG
- 53%
- Within 30%/30 mg/dL of BG
- 72%
Observational data: associations, not effects.
Further findings
Agreement between two sensors worn simultaneously
- Mean absolute difference
- 24 mg/dL (median 19 mg/dL)
- Mean RAD
- 14% (median 11%)
Sensor accuracy in non-ICU setting (1318 sensor-BG pairs)
- Mean difference
- 24 mg/dL (median 21 mg/dL)
- Mean RAD
- 21% (median 17%)
Original publication
Accuracy of Dexcom G6 Pro Continuous Glucose Monitor in the Intensive Care Setting: TIGHT ICU G6 Study. Diabetes Technol Ther. Published 13 August 2025. doi:10.
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