A population health analysis of trends in lower extremity amputation secondary to diabetes and peripheral artery disease, 2016–2023
Authors' conclusion
Racial, socioeconomic and gender disparities in amputation rates appear to be increasing despite reduced smoking and therapeutic improvements, reflecting increasing diabetes and PAD prevalence. Health systems and community partners should emphasize aggressive prevention including screening, early diagnosis and intensive risk factor management.
Study context
- Population
- Illinois residents with diabetes and peripheral artery disease (PAD) admitted to non-federal hospitals for lower extremity amputation, 2016–2023; excluded age <34 years, oncology or trauma-related diagnoses, isolated toe amputationsamputation admissions, 193 hospitals
- Participants
- 30,834 amputation admissions
- Outcome
- Changes in amputation rates and inpatient outcomes
- Follow-up
- 2016–2023
Methodological detailspopulation-based, Illinois Hospital Association COMPdata database
- Population-based
- Illinois Hospital Association COMPdata database
Main finding
As reported in the abstract
Amputation admissions · 2016 to 2023
Increase in amputation admissions between 2016 and 2023
65 %
Through foot amputations increase
129.4 %
Hi-Lo ratio decreased from 1.83 to
1.04
Observational data: associations, not effects.
Further findings
Largest percent increases in amputation rates by subgroup · 2016 to 2023
%
- Males
- +76.1
- Non-Hispanic Black patients
- +67.5
- Residents aged 65 to 74 years among the largest increases
Original publication
A population health analysis of trends in lower extremity amputation secondary to diabetes and peripheral artery disease, 2016–2023. Diabetes Res Clin Pract. Published 24 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →