Osteoporosis, bone & mineral

A 3-year retrospective analysis of patients admitted with clinical vertebral fragility fractures across hospitals in England, UK

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Hospitalised VFF patients represented a significant number, cost, and use of bed days. Those undergoing VA had a significantly shorter length of stay.

Study context

Population
Patients aged 55 years and over admitted with VFF to hospitals across England, 2017 to 201961% female
Participants
99,370 patients
Exposure
Patients aged over 75 years vs 55-74 years; vertebral augmentation vs conservative (non-surgical) management
  • Over 75 yearsn = 64,370
  • Vertebral augmentation (VA)n = 1,755
Outcome
Impact of VFF on hospitalisation: admissions, bed days, costs
Methodological detailshospital admissions database, England-wide
  • Hospital admissions database
  • England-wide

Main finding

As reported in the abstract

Hospitalisation for VFF
GroupValueBed daysCostMedian length of stay (MLOS)
Over 75 years65%1.5 million£465 million14.4 days
55-74 years659,000£239 million10.7 days

Value

Over 75 years65%
55-74 years— not stated in the abstract

Bed days

Over 75 years1.5 million
55-74 years659,000

Cost

Over 75 years£465 million
55-74 years£239 million

Median length of stay (MLOS)

Over 75 years14.4 days
55-74 years10.7 days
Average annual increase in admissions
14.3%

Observational data: associations, not effects.

Further findings

OutcomeVAConservative
VA vs conservative management44.2%65.1%
Median age (years)73.375.7
Share of total cohort1.8%— not stated in the abstract

— not stated in the abstract

  • VA vs conservative management: events/value = aged 75 years and over

Admission under non-surgical vs surgical speciality

Admitted under non-surgical speciality
84%
Median age, non-surgical vs surgical (years)
76.8 vs 67.6
MLOS, non-surgical vs surgical (days)
8.2 vs 6.0

VA vs conservative management

MLOS and cost per patient admission lower with VA than non-surgical management

Original publication

A 3-year retrospective analysis of patients admitted with clinical vertebral fragility fractures across hospitals in England, UK. Osteoporos Int. Published 6 January 2023. doi:10.1007/s00198-022-06647-w

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