CurrentEndo — Thyroid disease

Efficacy of machine learning model and EU-TIRADS-PL reporting system in predicting thyroid malignancy risk: a comparison

2026-11-14T06:45:51.583Z

Diagnostic or prognostic study · Endocr Pract, 2026.

Comprehensive Thyroid Assessment in a Prospective Japanese Cohort: A Cross-Sectional Baseline Analysis of Thyroid Function, Autoimmunity, and Ultrasonographic Findings

2026-11-13T19:45:41.967Z

Cross-sectional study · Thyroid, 2026.

Prevalence and Clinical Predictors of Subacute Thyroiditis in Patients with thyrotoxicosis: A Prospective Study

2026-11-13T18:46:09.627Z

Cohort study · Endocr Pract, 2026.

2026 ETA Consensus Statement on the Interpretation and Management of Calcitonin Levels in Patients with Thyroid Nodules

2026-11-13T17:46:43.542Z

Guideline or statement · Eur Thyroid J, 2026.

Efficacy and Safety of Radiofrequency Ablation for Solitary Autonomously Functioning Thyroid Nodules: A Systematic Review and Meta-Analysis

2026-11-13T17:46:43.542Z

Meta-analysis · Endocr Pract, 2026.

Clinical and Molecular Predictors of Malignancy in a Series of 585 RAS-positive Thyroid Nodules with Surgical Outcome

2026-11-13T17:00:16.153Z

Cohort study · J Clin Endocrinol Metab, 2026.

Treatment of Congenital Hypothyroidism: Impact of Secular Changes in Levothyroxine Initial Dose on Early Growth

2026-11-13T10:10:38.237Z

Cohort study · Horm Res Paediatr, 2022. thyroid-stimulating hormone (TSH), fT4, growth and treatment-related symptoms, first 2 years of life: TSH higher in children born in the 1980s vs those born later

Considerable interobserver variation calls for unambiguous definitions of thyroid nodule ultrasound characteristics

2026-11-13T10:09:06.606Z

Research article · Eur Thyroid J, 2023. Gwet's AC1 for the four most important features in decision-making: Irregular margins 0.34

Long-term follow-up result of antithyroid drug treatment of Graves’ hyperthyroidism in a large cohort

2026-11-13T10:09:06.606Z

Cohort study · Eur Thyroid J, 2023. First remission rate after ATD, median 72.7 months of follow-up: ATD 55.6%

Long-term outcome of thyroid abnormalities in patients with severe Covid-19

2026-11-13T10:09:06.606Z

Cohort study · Eur Thyroid J, 2023. Atypical thyroiditis at baseline (after excluding 63 patients on steroids before hospitalisation from TSH analysis) 12 (10%)

Multiple overlapping microwave ablation in benign thyroid nodule: a single-center 24-month study

2026-11-13T10:09:06.606Z

Cohort study · Eur Thyroid J, 2023. Volume reduction rate, months 1, 3, 6, 9, 12 and 24: Volume reduction rate, month 1 32%

Significance of FDG–PET standardized uptake values in predicting thyroid disease

2026-11-13T10:09:06.606Z

Cross-sectional study · Eur Thyroid J, 2023. Abnormal thyroid function by mean SUV — Mean SUV ≥ 2 vs Mean SUV < 2: RR 4.6

Survey on selenium clinical supplementation in autoimmune thyroid disease

2026-11-13T10:09:06.606Z

Cross-sectional study · Eur Thyroid J, 2023. Selenium serum concentration in general population unknown 80%

Dyslipidemia Is a Risk Factor for Hypothyroidism in Women: A Longitudinal Cohort Study from South Korea

2026-11-13T10:07:06.411Z

Cohort study · Thyroid, 2023. Hypothyroidism, median follow-up 61.0 months — Dyslipidemia vs No dyslipidemia: aHR (women) 2.05 (CI 1.31-3.19); p = 0.002; women

Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9

2026-11-13T10:07:06.411Z

Meta-analysis · Thyroid, 2023. Epigenome-wide significant CpG associations (p-value <1.1E-7), discovered and replicated: CpGs associated with free thyroxine 3

Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity

2026-11-13T10:07:06.411Z

Cohort study · Thyroid, 2023. Association of thyroid disorders with psychiatric disorders: Hypothyroidism and major depressive disorder (MDD), OR 1.31, p = 5.29 × 10-89

The Impact of Age- and Sex-Specific Reference Ranges for Serum Thyrotropin and Free Thyroxine on the Diagnosis of Subclinical Thyroid Dysfunction: A Multicenter Study from Japan

2026-11-13T10:07:06.411Z

Cross-sectional study · Thyroid, 2023. Age- and sex-specific TSH and fT4 levels: Median TSH, women in their 30s, Siemens kit (2.5th; 97.5th percentile 0.5; 4.6) 1.5 mIU/L

Incidence of and Risk Factors for Neonatal Hypothyroidism Among Women with Graves' Disease Treated with Antithyroid Drugs Until Delivery

2026-11-13T10:07:06.411Z

Cohort study · Thyroid, 2023. Neonatal hypothyroidism, at delivery: MMI 12 (19.0% (CI 11.2-30.4)) · PTU 31 (12.8% (CI 9.2-17.6))

Iodinated Contrast Administration and Risks of Thyroid Dysfunction: A Retrospective Cohort Analysis of the U.S. Veterans Health Administration System

2026-11-13T10:07:06.411Z

Cohort study · Thyroid, 2023. Thyroid dysfunction: Iodine contrast 4.8% · No iodine exposure 3.6%

M1-Like Macrophages Modulate Fibrosis and Inflammation of Orbital Fibroblasts in Graves' Orbitopathy: Potential Relevance to Soluble Interleukin-6 Receptor

2026-11-13T10:07:06.411Z

Case-control study · Thyroid, 2023. GO orbital connective tissues displayed increased IL-6, sIL-6R, STAT3 and IL-17A levels

Risk of Permanent Hypoparathyroidism Requiring Calcitriol Therapy in a Population-Based Cohort of Adults Older Than 65 Undergoing Total Thyroidectomy for Graves' Disease

2026-11-13T10:07:06.411Z

Cohort study · Thyroid, 2022. Permanent hypoparathyroidism requiring calcitriol therapy: Patients with permanent hypoparathyroidism 104 (2.2% [95% CI 1.8-2.7%])

The Free Triiodothyronine/Free Thyroxine Ratio Is Associated with Frailty in Older Adults: A Longitudinal Multisetting Study

2026-11-13T10:07:06.411Z

Secondary analysis · Thyroid, 2023. fT3/fT4 ratio vs Frailty Index: Inverse correlation, fT3/fT4 ratio vs FI -0.17 (ρs; CI -0.092 to 0.252; p < 0.001)

Thyroidal Angiotensin-Converting Enzyme 2 Protein Expression and Thyroid Function Tests in Patients with COVID-19: Results from a Retrospective Case Series and a Prospective Cohort Study

2026-11-13T10:07:06.411Z

Cohort study · Thyroid, 2023. Thyroidal ACE2 protein expression: Deceased COVID-19 87%

Ultrasound Follow-Up of Benign Thyroid Nodules: A Scoping Review

2026-11-13T10:07:06.411Z

Research article · Thyroid, 2023. Likelihood of malignancy: >4 years 1 (0.4%) · 1–2 years 2 (0.3%)

High Thyrotropin Levels and Risk of Mortality in the Elderly With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis

2026-11-13T10:04:31.875Z

Meta-analysis · Endocr Pract, 2022. SCH vs Euthyroid: pooled HR 1.18 (95% CI 0.95, 1.45); All-cause mortality; I2 = 94%

Increased Incidence and Severity of New Graves Disease Diagnoses in Youth During the COVID-19 Pandemic

2026-11-13T10:04:31.875Z

Cohort study · Endocr Pract, 2023. Incidence of new-onset GD — Pandemic vs Pre-pandemic; P = .01; increased incidence during pandemic

Long-Term Follow-up of Graves Orbitopathy After Treatment With Short- or Long-Term Methimazole or Radioactive Iodine

2026-11-13T10:04:31.875Z

Cohort study · Endocr Pract, 2023. Worsening and de novo development of GO, >18 to 234 months: Radioiodine 26 (9.9%) · LT-MMI 8 (4.5%)

Predictors of Prolonged Euthyroidism After Radioactive Iodine Treatment for Graves’ Disease: A Pilot Study

2026-11-13T10:04:31.875Z

Cohort study · Endocr Pract, 2022. Outcome after RAI: Prolonged euthyroidism > 12 months 18 (21.2%)

Ultrasound-Based Risk Stratification System for the Assessment of Partially Cystic Thyroid Nodules

2026-11-13T10:04:31.875Z

Diagnostic or prognostic study · Endocr Pract, 2023. Nomogram performance for malignancy: Training data set: AUC 0.860; sensitivity 77.1%; specificity 84.7% · External validation data set: AUC 0.897; sensitivity 91.7%; specificity 87.0%

A prospective comparison of ACR‐TIRADS and EU‐TIRADS in thyroid nodule assessment for FNA‐US

2026-11-13T09:59:57.591Z

Diagnostic or prognostic study · Clin Endocrinol (Oxf), 2022. Diagnostic accuracy (168 nodules, 149 patients with conclusive results): ACR-TIRADS: Sensitivity 100.0%; Specificity 28.7%; NPV 100.0%; False negative 0.0% · EU-TIRADS: Sensitivity 90.0%; Specificity 19.1%; NPV 96.8%; False negative 9.1% (n = 1)

Comparison of reproductive outcomes in subclinical hypothyroidism women with high‐normal versus low‐normal thyroid‐stimulating hormone levels after treatment with levothyroxine

2026-11-13T09:59:57.591Z

Cohort study · Clin Endocrinol (Oxf), 2022. Clinical pregnancy, miscarriage and live birth rates — High-normal vs Low-normal: aOR (miscarriage) 2.27 (95% CI 0.77-6.69); p = .14; adjusted by age, anti-Mullerian hormone (AMH), infertility duration, transferred embryos, LT4 dose and duration

Consensus statement on the management of incidentally discovered FDG avid thyroid nodules in patients being investigated for other cancers

2026-11-13T09:59:57.591Z

Guideline or statement · Clin Endocrinol (Oxf), 2023.

Different FT3/TSH correlation in acquired and congenital hypothyroid patients reveals a different hypothalamic set‐point

2026-11-13T09:59:57.591Z

Cohort study · Clin Endocrinol (Oxf), 2022. Daily weight-based l-T4 dose: CH 1.9 mcg/kg · TP 1.7 mcg/kg

Endocrine complications after hematopoietic stem cell transplantation during childhood—Results from a close follow‐up in a cohort of 152 patients

2026-11-13T09:59:57.591Z

Cohort study · Clin Endocrinol (Oxf), 2022. Endocrine complications after HSCT, follow-up 9.9 (IQR: 12.2) years: At least one endocrine complication 65.1%

Increased workload without clinical benefit: Results following implementation of the ACR‐TIRADS system for thyroid nodules

2026-11-13T09:59:57.591Z

Research article · Clin Endocrinol (Oxf), 2023. Proportion of cancers/FNA: Post-TIRADS 9.9% · Pre-TIRADS 8.7%

Iodine status in Danish pregnant women after an increase in iodine fortification

2026-11-13T09:59:57.591Z

Cross-sectional study · Clin Endocrinol (Oxf), 2022. Median UIC: 2021 median 77 (95% CI 61-96) µg/L · 2012 median 101 (95% CI 89-111) µg/L

Long‐term outcomes of anti‐thyroid drug treatment in childhood‐onset Graves' disease

2026-11-13T09:59:57.591Z

Cohort study · Clin Endocrinol (Oxf), 2023. median 7.1 (3.8, 10.9) years since diagnosis: Remission rate 21% (56 out of 265 patients)

Nomogram to differentiate benign and malignant thyroid nodules in the American College of Radiology Thyroid Imaging Reporting and Data System level 5

2026-11-13T09:59:57.591Z

Diagnostic or prognostic study · Clin Endocrinol (Oxf), 2022. Differentiation of benign and malignant TR5 nodules: Nomogram: AUC (primary cohort) 0.786 (95% CI 0.742-0.830); AUC (external validation cohort) 0.712 (95% CI 0.615-0.809); specificity 0.783 · ACR score model: AUC 0.626; specificity 0.391

Preconceptual thyroid peroxidase antibody positivity in women with recurrent pregnancy losses may contribute to an increased risk for another miscarriage

2026-11-13T09:59:57.591Z

Secondary analysis · Clin Endocrinol (Oxf), 2022. All first-trimester miscarriages — TPO-ab positive vs TPO-ab negative: OR 1.60 (95% CI 0.99-2.57)

Thyroid function in infants born to women with hypothyroidism: An observational study at an Australian tertiary perinatal centre

2026-11-13T09:59:57.591Z

Cohort study · Clin Endocrinol (Oxf), 2023. Thyroid function, 2 weeks of age: Normal thyroid function 780 infants (99%)

Application of machine learning methods to guide patient management by predicting the risk of malignancy of Bethesda III-V thyroid nodules

2026-11-13T09:58:18.729Z

Diagnostic or prognostic study · Eur J Endocrinol, 2023. Diagnostic performance in the validation cohort: LR: specificity 90%; sensitivity 57.3%; PPV 73.4%; NPV 81.4%; AUC 84% (95% CI 78.5%-89.5%) · RF: specificity 87.6%; sensitivity 54.7%; PPV 68.1%; NPV 80%; AUC 82.6% (95% CI 77.4%-87.9%)

Variation in the reference range limits of thyroid function tests and association with the prevalence of levothyroxine treatment

2026-11-13T09:58:18.729Z

Research article · Eur J Endocrinol, 2023. Prevalent LT4 treatment by reference interval limits: Upper limit of serum TSH: significantly, linearly, independently and negatively associated with prevalent LT4 treatment -0.54% (95% CI, -0.68% to -0.40%)

Association Between Systemic Lupus Erythematosus and Primary Hypothyroidism: Evidence from Complementary Genetic Methods

2026-11-13T09:55:31.327Z

Diagnostic or prognostic study · J Clin Endocrinol Metab, 2022. Causal association between SLE and primary hypothyroidism: Genetic correlation between SLE and primary hypothyroidism (LD score regression), P = 6.00 × 10-4 0.2488

Maternal Thyroid Dysfunction and Neuropsychological Development in Children

2026-11-13T09:55:31.327Z

Cohort study · J Clin Endocrinol Metab, 2022. Neuropsychological development scores vs children of euthyroid mothers, 6 and 24 months: Overt hypothyroidism: lower personal-social domain score, girls, 6 months 7.0 points (95% CI, 1.7-12.4)

Novel Causal Plasma Proteins for Hypothyroidism: A Large-scale Plasma Proteome Mendelian Randomization Analysis

2026-11-13T09:55:31.327Z

Diagnostic or prognostic study · J Clin Endocrinol Metab, 2022. Causal plasma proteins for hypothyroidism: Proteins identified in discovery cohort 31

Teprotumumab-Related Hyperglycemia

2026-11-13T09:55:31.327Z

Cohort study · J Clin Endocrinol Metab, 2022. 3 months (HbA1c): Diabetes least-squares mean change 1.3; P P < .001 · Prediabetes least-squares mean change 0.7; P P = .01 · Normoglycemia least-squares mean change 0.1; P P = .41

Integration of Artificial Intelligence Decision Aids to Reduce Workload and Enhance Efficiency in Thyroid Nodule Management

2026-11-13T05:29:11.680Z

Diagnostic or prognostic study · JAMA Netw Open, 2023. Mean task completion time: Junior reader 11: all-AI vs optimized (increased with optimized) 15.2 seconds (95% CI, 13.2-17.2) to 19.4 seconds (95% CI, 15.6-23.3)

Coxa Vara Deformity in Fibrous Dysplasia/ McCune‐Albright Syndrome: Prevalence, Natural History and Risk Factors: A Two‐Center Study

2026-11-13T05:25:44.610Z

Case-control study · J Bone Miner Res, 2023. Prevalence of varus deformity: Femurs with varus deformity 99 (36%)

Relapse of Graves' disease in Chinese children: a retrospective cohort study

2026-11-13T04:56:16.556Z

Cohort study · Eur Thyroid J, 2023. Remission and relapse after remission: Remission 79 (38.7%)

Voice and swallowing symptoms after thyroid surgery assessed using the ThyVoice online platform

2026-11-13T04:56:16.556Z

Cohort study · Eur Thyroid J, 2023. VHI preop 41 ± 15