CurrentEndo — Obesity

Perinatal maternal and child growth mediate the association between maternal education and children’s overweight/obesity in Europe: the Feel4Diabetes-study

2026-11-14T10:46:26.825Z

Cross-sectional study · Int J Obes (Lond), 2026.

Kidney effects of tirzepatide across albuminuria, filtration markers, and clinical outcomes: a parent-trial-level systematic review and meta-analysis

2026-11-14T06:45:51.583Z

Meta-analysis · Diabetes Res Clin Pract, 2026.

Cardiovascular Outcomes in Semaglutide Versus Tirzepatide Users With Obesity and Atherosclerotic Disease: A Target Trial Emulation

2026-11-13T18:46:09.627Z

Research article · Diabetes Obes Metab, 2026.

Effect of subnormal estimated glomerular filtration rate on mortality varies by obesity metrics: a two-dimensional exposure–response analysis

2026-11-13T18:46:09.627Z

Research article · Int J Obes (Lond), 2026.

Effects of semaglutide on cardiac structure and function in heart failure with preserved ejection fraction and obesity: a pre-specified cardiac magnetic resonance substudy of the CAMEO-SEMA trial

2026-11-13T18:46:09.627Z

Secondary analysis · Nat Med, 2026.

Hemodynamic effects of semaglutide in individuals with heart failure with preserved ejection fraction and obesity: a placebo-controlled randomized clinical trial

2026-11-13T18:46:09.627Z

Randomized controlled trial · Nat Med, 2026.

Insomnia versus daytime sleepiness: distinct behavioural phenotypes of mood and binge eating in adults with clinical obesity

2026-11-13T18:46:09.627Z

Cross-sectional study · Int J Obes (Lond), 2026.

Longitudinal Associations of Changes in Body Mass Index and Waist‐to‐Height Ratio With Cardiometabolic Risk Factors: Sex‐Specific Analyses in UK Biobank

2026-11-13T18:46:09.627Z

Cohort study · Diabetes Obes Metab, 2026.

Metabolic Bariatric Surgery Leads to Similar Benefits for Diabetes Management and Glycaemia in Remitters and Non‐Remitters

2026-11-13T18:46:09.627Z

Cohort study · Diabetes Obes Metab, 2026.

Phase 3 clinical development of semaglutide (2015-2026): a comprehensive evidence-based review of trial designs, therapeutic outcomes and global clinical experience

2026-11-13T18:46:09.627Z

Research article · Diabetes Res Clin Pract, 2026.

Rethinking obesity: comparison of the new clinical obesity framework with traditional BMI-based classifications in midlife UK adults

2026-11-13T18:46:09.627Z

Cohort study · Int J Obes (Lond), 2026.

Screening for Nutritional Risk in Adults Receiving Obesity Treatment: A Systematic Literature Review of Available Tools and Identification of Conceptual Gaps

2026-11-13T18:46:09.627Z

Meta-analysis · Diabetes Obes Metab, 2026.

Trevogrumab (anti-GDF8) with or without garetosmab (anti-activin A) for prevention of muscle loss during semaglutide-induced weight reduction in people with obesity (COURAGE): a two-part, phase 2, double-blind, placebo-controlled, randomised trial

2026-11-13T18:46:09.627Z

Randomized controlled trial · Lancet, 2026.

Association Between Orforglipron and Blood Pressure in Adults With Obesity With or Without Type 2 Diabetes: Post Hoc Analyses From ATTAIN‐1 and ATTAIN‐2 Trials

2026-11-13T17:46:43.542Z

Secondary analysis · Diabetes Obes Metab, 2026.

Orforglipron for Obstructive Sleep Apnea: Results From 2 Randomized Clinical Trials (ATTAIN-OSA)

2026-11-13T17:46:43.542Z

Randomized controlled trial · JAMA, 2026.

A scoping review of long-term childhood outcomes evaluated in preconception and antenatal intervention strategies for the prevention of childhood obesity (COS-PEACH)

2026-11-13T17:00:16.153Z

Research article · Int J Obes (Lond), 2026.

Real-world effectiveness of tirzepatide in individuals with obesity: weight response, treatment-related factors and diabetes status

2026-11-13T17:00:16.153Z

Cohort study · Diabetes Metab, 2026.

Resistance exercise to attenuate lean mass loss during tirzepatide therapy for obesity: a randomized controlled trial

2026-11-13T17:00:16.153Z

Randomized controlled trial · Nat Med, 2026.

Retatrutide Once Weekly in Adults with Knee Osteoarthritis Pain and Obesity

2026-11-13T17:00:16.153Z

Research article · N Engl J Med, 2026.

Adipose Tissue Regulation of Vitamin B12 Uptake and the CD320 Receptor–TCN2 Transport Axis in Pregnancy

2026-11-13T15:47:59.646Z

Research article · J Clin Endocrinol Metab, 2026.

Cardiovascular outcomes with survodutide in adults with obesity at increased cardiovascular risk (SYNCHRONIZE-CVOT): a double-blind, randomised, placebo-controlled, phase 3 trial

2026-11-13T15:47:59.646Z

Randomized controlled trial · Lancet, 2026.

Effect of Semaglutide on Dumping Syndrome and Post-Bariatric Hypoglycemia After Roux-en-Y Gastric Bypass: A Single-Center Retrospective Study

2026-11-13T15:47:59.646Z

Cohort study · Endocr Pract, 2026.

Stroke outcomes in patients with obesity undergoing recanalization therapy

2026-11-13T15:47:59.646Z

Cohort study · Int J Obes (Lond), 2026.

Effectiveness of Goal-Directed and Outcome-Based Financial Incentives for Weight Loss in Primary Care Patients With Obesity Living in Socioeconomically Disadvantaged Neighborhoods: A Randomized Clinical Trial

2026-11-13T11:02:34.619Z

Randomized controlled trial · JAMA Intern Med, 2023. ≥5% weight loss (adjusted proportion), 6 months: Resources-only 22.1% · Goal-directed 39.0% · Outcome-based 49.1%

Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention

2026-11-13T11:02:00.546Z

Cohort study · Nat Med, 2023. Multiomic signatures of body mass index (BMI): Atlas of cross-sectional and longitudinal changes in blood analytes associated with BMI variation 1,111 blood analytes

Assessment of the Risk Evaluation and Mitigation Strategy (REMS) for Phentermine–Topiramate to Prevent Exposure During Pregnancy

2026-11-13T11:01:36.927Z

Cohort study · Ann Intern Med, 2023. Prenatal exposure — Phentermine-topiramate vs Topiramate: prevalence ratio (pregnancy at treatment initiation; 0.9 vs 1.6 per 1000 episodes) 0.54 (95% CI 0.31 to 0.95); adjusted

Association of Physical Activity and Screen Time With Body Mass Index Among US Adolescents

2026-11-13T11:00:06.281Z

Cross-sectional study · JAMA Netw Open, 2023. Overweight or obesity risk (models including both screen time and step count) — Medium screen time vs Low screen time: RR 1.24 (95% CI 1.12-1.37)

Effect of a Plant-Based vs Omnivorous Soul Food Diet on Weight and Lipid Levels Among African American Adults: A Randomized Clinical Trial

2026-11-13T11:00:06.281Z

Randomized controlled trial · JAMA Netw Open, 2023. Change in weight, 12 months: Vegan mean -2.39 (95% CI -3.48 to -1.30) kg · Omni -2.03 (95% CI -3.07 to -1.00) kg

The Role of Prenatal Psychosocial Stress in the Associations of a Proinflammatory Diet in Pregnancy With Child Adiposity and Growth Trajectories

2026-11-13T11:00:06.281Z

Cohort study · JAMA Netw Open, 2023. Adiposity trajectories, highest vs lowest DII quartile (adjusted), over time — DII quartile 4 vs DII quartile 1: β, BMI z change 0.03 SD units/y (95% CI 0.01-0.05); slower decrease in BMI z

Trends in the Prevalence of Metabolically Healthy Obesity Among US Adults, 1999-2018

2026-11-13T11:00:06.281Z

Cross-sectional study · JAMA Netw Open, 2023. Age-standardized prevalence of MHO, all adults: 1999-2002 3.2% (95% CI 2.6%-3.8%) · 2015-2018 6.6% (95% CI 5.3%-7.9%)

Cord Blood Plasma Metabolome-wide Associations With Height From Birth to Adolescence

2026-11-13T10:57:18.358Z

Cohort study · J Bone Miner Res, 2023. Cord plasma metabolites and attained height and height trajectories, birth to adolescence: Attained height in early (0-4 y) and middle (6-12 y) childhood associated with TAGs, DAGs, CEs, phospholipids, AAs, ACs and nucleotides

A randomized trial comparing diet and delivery strategies for weight management in adolescents with intellectual disabilities

2026-11-13T10:54:04.269Z

Randomized controlled trial · Pediatr Obes, 2022. Weight change, 12 months: RD/eSLD -7.0% · RD/CD -1.1% · FTF/CD +1.1%

Adolescent overweight and obesity in Ireland—Trends and sociodemographic associations between 1990 and 2020

2026-11-13T10:54:04.269Z

Cross-sectional study · Pediatr Obes, 2022. Overweight/obesity prevalence: 2020 24% · 2006 18% · 1990 13%

An addiction‐based digital weight loss intervention: A multi‐centre randomized controlled trial

2026-11-13T10:54:04.269Z

Randomized controlled trial · Pediatr Obes, 2022. Change in %BMIp95, 24-weeks — between App intervention with coaching and App intervention without coaching; p = 0.3; no significant weight loss difference between groups, including in-person multidisciplinary obesity intervention

Association between dietary inflammatory index and anthropometric indicators of adiposity in Brazilian adolescents

2026-11-13T10:54:04.269Z

Cross-sectional study · Pediatr Obes, 2023. Overweight, abdominal obesity and high WHtR (4th vs 1st DII quartile) — 4th quartile of DII vs 1st quartile: OR 1.76 (95% CI 1.37; 2.25); Overweight, boys

Association between gestational weight gain and risk of overweight at 3 years old: The Japan Environment and Children's Study

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2022. Overweight at 3 years — Per 5 kg increase of GWG: multivariable RR 1.21 (95% CI 1.17-1.25)

Association of a primary care‐based mobile food pantry with child body mass index: A propensity score matched cohort study

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2023. Change in child BMIz, follow-up period — Food FARMacia vs Non-participants: unadjusted difference-in-differences (DiD) -0.28 (CI -0.52, -0.04); smaller BMIz increases with Food FARMacia

Association of gut microbiota and glucose metabolism in children with disparate degrees of adiposity

2026-11-13T10:54:04.269Z

Cross-sectional study · Pediatr Obes, 2023. Gut microbiota composition (LEfSe) and correlations with glucose metabolism and inflammatory markers — Mild obesity vs Severe obesity; p < 0.05; more Fusobacteria (phylum), Alistipes (genus); fewer Granulicatella and Clostridium (genus) with mild obesity

Association of intestinal microbiota and its metabolite markers with excess weight in Chinese children and adolescents

2026-11-13T10:54:04.269Z

Cross-sectional study · Pediatr Obes, 2023. Intestinal microbiota (16S rRNA sequencing): Alpha diversity significantly higher in normal-weight vs overweight/obese

Associations between eating behaviours and cardiometabolic risk among adolescents in the Health Outcomes and Measures of the Environment study

2026-11-13T10:54:04.269Z

Cross-sectional study · Pediatr Obes, 2022. Cardiometabolic risk score by eating behaviour subscale (multivariable linear regression): Emotional overeating: ß (95% CI), higher risk 1.34 (0.67, 2.01)

Associations between maternal metabolic parameters during pregnancy and fetal and child growth trajectories from 20 weeks' gestation to 5 years of age: Secondary analysis from the ROLO longitudinal birth cohort study

2026-11-13T10:54:04.269Z

Secondary analysis · Pediatr Obes, 2022. Weight and abdominal circumference trajectories, 20 weeks gestation to 5 years: No strong evidence of associations between any maternal metabolic parameters and fetal to childhood weight and abdominal circumference trajectories

Associations of maternal insulin sensitivity during pregnancy with childhood central adiposity in the Genetics of Glucose regulation in Gestation and Growth (Gen3G) cohort

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2022. Association of maternal insulin sensitivity with child adiposity, ~5 years: Univariate correlation of lower maternal insulin sensitivity with greater child adiposity (anthropometry, DXA total and trunk % fat), r -0.122 to -0.159

Associations of cord blood leukocyte telomere length with adiposity growth from infancy to adolescence

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2022. Age of BMI peak (females) — Short LTL: β 0.99 (95% CI 0.16, 1.82); psex interaction = 0.015; later age of peak for females

Change in parent and child psychopathology following obesity treatment and maintenance: A secondary data analysis

2026-11-13T10:54:04.269Z

Secondary analysis · Pediatr Obes, 2022. Children: significant reductions from baseline to post-FBT in all forms of psychopathology, and from post-FBT to post-maintenance in general psychopathology

Childhood follow‐up of the GRoW randomized trial: Metformin in addition to dietary and lifestyle advice for pregnant women with overweight or obesity

2026-11-13T10:54:04.269Z

Randomized controlled trial · Pediatr Obes, 2022. BMI >85th centile, all time points: Number of children with BMI >85th centile similar between treatment groups at all time points

Childhood sleep and obesity risk: A prospective cohort study of 10 000 Swedish children

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2022. Sleep duration early in life and later BMI Z-scores: Sleep duration early in life negatively associated with later BMI Z-scores (adjusted β, 95% CI (-0.15) - (-0.03), p = 0.005) -0.09

Children's activity and diet behaviours in the summer holidays versus school year

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2023. Summer holidays vs School year: difference in moderate- to vigorous-physical activity -12 min/day; p = 0.001

Circadian variation of serum leptin and adipose tissue changes in children

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2022. Circadian leptin variables vs change in TBFM, %FM, TrFM: None of the circadian leptin variables was significantly associated with change in TBFM, %FM or TrFM

Combined intake of sugar‐sweetened beverages and sugar‐containing ultra‐processed foods is associated with an increase in body mass index during early childhood

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2023. Change in BMIz, 2 years: SSB and SUP foods intake (in combination but not individually) in both waves, β coefficient 0.13 (95% CI: 0.02, 0.23)

Cross‐sectional and longitudinal associations between family meals frequency and children's overweight/obesity in families at high risk of type 2 diabetes: The Feel4Diabetes ‐ study

2026-11-13T10:54:04.269Z

Cohort study · Pediatr Obes, 2023. Overweight/obesity at follow-up — ≥3 family breakfasts and/or dinners/week vs Lower frequency: OR 0.65 (95% CI 0.41, 0.96); boys