Type 2 & other diabetes

Zero Dollar Drug Copay program improves antidiabetic medication adherence and medication use patterns among Blue Cross and Blue Shield of Louisiana members with diabetes in Louisiana

BMJ Open Diabetes Res CarePublished Retrospective cohort study

Authors' conclusion

A zero-dollar co-pay pharmacy benefit improved antidiabetic medication adherence and increased medication use among BCBSLA members with diabetes.

Study context

Population
Continuously enrolled Blue Cross and Blue Shield of Louisiana (BCBSLA) members with diabetes, claims 2019–2021; mean age 48.8 (SD 12.5) years ZDC and 52.9 (SD 11.3) years controls
Participants
7,603 participants
Exposure
Zero-dollar co-pay pharmacy benefit vs no ZDC coverage
  • ZDCn = 3,045
  • Controln = 4,558reference
Outcome
Antidiabetic medication adherence and use (all medications)
Follow-up
July 1, 2020, to December 31, 2021
Methodological detailspropensity score odds weights, weighted difference-in-differences with individual and time fixed effects
  • Propensity score odds weights
  • Weighted difference-in-differences with individual and time fixed effects

Main finding

As reported in the abstract

Difference-in-differences, monthly proportion of days covered (PDC)

4.4 percentage points

P < 0.001

ZDC

Difference-in-differences, monthly medication use

6.2 percentage points

P < 0.001

ZDC

Difference-in-differences, drug counts

0.090

P < 0.001

ZDC

Observational data: associations, not effects.

Further findings

OutcomeEstimateP value
ZDC-eligible medicationsZDC vs Control · increase with ZDCdifference-in-differences, PDC 5.4 percentage pointsall p<0.001
ZDC-eligible medicationsZDC vs Control · increase with ZDCdifference-in-differences, monthly use 7.6 percentage pointsall p<0.001
ZDC-eligible medicationsZDC vs Control · increase with ZDCdifference-in-differences, drug counts 0.074all p<0.001

Subgroups: pre-ZDC users, complex users, pre-ZDC non-users

Improvements among pre-ZDC users and complex users, but not among pre-ZDC non-users

Original publication

Zero Dollar Drug Copay program improves antidiabetic medication adherence and medication use patterns among Blue Cross and Blue Shield of Louisiana members with diabetes in Louisiana. BMJ Open Diabetes Res Care. Published 20 January 2026. doi:10.1136/bmjdrc-2025-005146

Composed by AI from the published abstract and checked against it. How Briefs are made →

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