Obesity

Variation in executive function relates toBMIincreases in youth who were initially of a healthy weight in theABCDStudy

Obesity (Silver Spring)Published Longitudinal cohort study

Authors' conclusion

Underlying variation in EF and cognition may be important for weight gain, but 2 years of weight gain may not be enough to have clinical implications for EF and cognition beyond inhibitory control. These findings suggest that more attention should be paid to the inclusion of EF programs in obesity prevention efforts.

Study context

Population
Youth aged 9–12 years in the Adolescent Brain Cognitive Development (ABCD) Study (release 4.0), all of healthy weight at baseline (9/10 years old); 12.4% had unhealthy weight by ages 11/12 years
Participants
2,794 participants
Outcome
Whether variation in executive function (EF) and cognition precedes weight gain (BMI ~ EF × Time) or weight gain causes changes to EF and cognition (EF ~ BMI × Time)
Follow-up
9 to 12 years old
Methodological detailsnested random-effects mixed models, adjusted for sex, puberty and caregiver education, random effects for site and subject
  • Nested random-effects mixed models
  • Adjusted for sex, puberty and caregiver education
  • Random effects for site and subject

Main finding

As reported in the abstract

  • Variation in impulsivity, memory, learning and processing speed associated with greater increases in BMI trajectories
  • Weight gain associated with a decrease in inhibitory control; no other associations observed

Observational data: associations, not effects.

Original publication

Variation in executive function relates toBMIincreases in youth who were initially of a healthy weight in theABCDStudy. Obesity (Silver Spring). Published 20 September 2023. doi:10.1002/oby.23811

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