Type 2 diabetes mellitus in people with intellectual disabilities: Examining incidence, risk factors, quality of care and related complications. A population-based matched cohort study
Main finding · Incidence of T2DMResult — go to the resultAdjusted incidence rate ratio 6.91 95 % CI 5.81–8.22Authors' conclusion
People with intellectual disabilities are at increased risk of T2DM at younger ages, have specific risk factors, experience inequities in care and are at risk for macrovascular complications.
Study context
- Population
- People with intellectual disabilities and matched controls; electronic health-record data Jan 2010 to May 2022matched cohort
- Participants
- 189,172 vs 306,697
- Exposure
- People with intellectual disabilities vs matched controls
- Intellectual disabilitiesn = 189,172
- Controlsn = 306,697reference
- Outcome
- Incidence of T2DM (per 1,000 person-years)
Methodological detailsmatched on age, sex and family practice, electronic health-record data
- Matched on age, sex and family practice
- Electronic health-record data
Main finding
Incidence of T2DM
Adjusted incidence rate ratio
6.91
95 % CI 5.81–8.22
By group
Intellectual disabilitiesvs Controls
adjusted IRR 6.91 (95 % CI 5.81–8.22)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Risk factor for T2DM in intellectual disabilities: impaired mobility
- Impaired mobility associated with T2DM incidence, OR (5.87-10.15)
- 7.72
Quality of care
- People with intellectual disabilities received HbA1c and cholesterol tests, and eye and foot examinations less often
Macrovascular complications
- Higher risk of developing macrovascular complications in people with intellectual disabilities
- 12 %
Original publication
Type 2 diabetes mellitus in people with intellectual disabilities: Examining incidence, risk factors, quality of care and related complications. A population-based matched cohort study. Diabetes Res Clin Pract. Published 7 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →