ThyroidPrint: Thyroid Genetic Classifier Long‐Term Follow‐Up of Benign Called Lesions
Authors' conclusion
Long-term follow-up demonstrates that ThyroidPrint provides a reliable, safe and durable approach to managing ITN, significantly reducing unnecessary surgeries while maintaining a low rate of missed malignancies. These findings reinforce its role in personalised patient management and support structured surveillance protocols for selected patients.
Study context
- Population
- Patients with indeterminate thyroid nodules (Bethesda III/IV) and a previous benign ThyroidPrint (qPCR-based 10-gene classifier) result, managed via active surveillance
- Participants
- 104 patients
- Outcome
- Remained under active surveillance
- Follow-up
- 5 years
Methodological detailssingle-centre, long-term follow-up, Surgery reserved for significant nodule growth or patient preference; US monitoring and clinical assessments guided management
- Single-centre
- Long-term follow-up
- Surgery reserved for significant nodule growth or patient preference; US monitoring and clinical assessments guided management
Main finding
As reported in the abstract
Benign ThyroidPrint
94.2%
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Surgery · 5 years | Benign ThyroidPrint 5.8% |
Surgery · 5 years
- All resected nodules had benign or low-risk histology
Safety
- False-negative rate was minimal among resected nodules
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
ThyroidPrint: Thyroid Genetic Classifier Long‐Term Follow‐Up of Benign Called Lesions. Clin Endocrinol (Oxf). Published 22 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →