The value of loss of protective pain sensation in predicting a first ulceration of the foot in people with diabetes
Main finding · First ever ulcer (FEU)Result — go to the resultAge-sex-adjusted HR 3.0Authors' conclusion
It is suggested that estimation of LOPP is included in routine practice because of its high predictive value for a FEU.
Study context
- Population
- People with diabetes and loss of protective sensation (LOPS), without history of first ever ulcer (FEU), presenting in a specialist clinic
- Participants
- 130 people
- Exposure
- Loss of protective pain (LOPP) vs no LOPP
- Outcome
- Risk of first ever foot ulcer (FEU) and time to onset
- Follow-up
- Median 48.3 months
Methodological detailssingle specialist clinic
- Single specialist clinic
Main finding
First ever ulcer (FEU) · median 48.3 months
Age-sex-adjusted HR
3.0
P = 0.02
Events by group
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prevalence of loss of pain perception
- Pain perception lost
- 55.4%
Original publication
The value of loss of protective pain sensation in predicting a first ulceration of the foot in people with diabetes. Diabet Med. Published 30 October 2023. doi:10.
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