Pituitary & hypothalamus

The Stress-Induced Hyperprolactinemia Might Not Be that Stress-Induced as Argued: Observational Case-Control Study

Endocr PractPublished Observational case-control study

Authors' conclusion

Si-HP is independent of states momentary or trait anxiety, and phobias trypanophobia, nosocomephobia and scanxiety. In this context, the relevance of the nomenclature of si-HP is controversial.

Study context

Population
Individuals referred for hyperprolactinemia (9 males, 82 females)9 males · 82 females
Participants
91 individuals
Comparison
Venous cannula (VC) vs venous puncture (VP) serial prolactin (PRL) sampling; Stress-induced hyperprolactinemia (si-HP) vs other groups
  • VCn = 32
  • VPn = 59
Outcome
Frequency of si-HP, defined as PRL at 60 min decreasing to normal limits according to gender
Follow-up
60 min

Main finding

As reported in the abstract

Frequency of si-HP

VC

7 of 32

7 of 32

VP

12 of 59

12 of 59

P = 0.9

Observational data: associations, not effects.

Further findings

PRL0min and PRL60min levels, VC vs VP

PRL0min and PRL60min similar in VC and VP

Anxiety and phobia scores (trypanophobia, nosocomephobia, scanxiety, ASI-3, STAI-1, STAI-2), si-HP vs other groups

Scores similar between si-HP and other groups

Correlation of anxiety and phobia scores with PRL0min or PRL60min

Scale scores not correlated with PRL0min or PRL60min

Original publication

The Stress-Induced Hyperprolactinemia Might Not Be that Stress-Induced as Argued: Observational Case-Control Study. Endocr Pract. Published 5 November 2024. doi:10.1016/j.eprac.2024.10.013

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