The Stress-Induced Hyperprolactinemia Might Not Be that Stress-Induced as Argued: Observational Case-Control Study
Authors' conclusion
Si-HP is independent of states momentary or trait anxiety, and phobias trypanophobia, nosocomephobia and scanxiety. In this context, the relevance of the nomenclature of si-HP is controversial.
Study context
- Population
- Individuals referred for hyperprolactinemia (9 males, 82 females)9 males · 82 females
- Participants
- 91 individuals
- Comparison
- Venous cannula (VC) vs venous puncture (VP) serial prolactin (PRL) sampling; Stress-induced hyperprolactinemia (si-HP) vs other groups
- VCn = 32
- VPn = 59
- Outcome
- Frequency of si-HP, defined as PRL at 60 min decreasing to normal limits according to gender
- Follow-up
- 60 min
Main finding
As reported in the abstract
Frequency of si-HP
VC
7 of 32
7 of 32
VP
12 of 59
12 of 59
P = 0.9
Observational data: associations, not effects.
Further findings
PRL0min and PRL60min levels, VC vs VP
- PRL0min and PRL60min similar in VC and VP
Anxiety and phobia scores (trypanophobia, nosocomephobia, scanxiety, ASI-3, STAI-1, STAI-2), si-HP vs other groups
- Scores similar between si-HP and other groups
Correlation of anxiety and phobia scores with PRL0min or PRL60min
- Scale scores not correlated with PRL0min or PRL60min
Original publication
The Stress-Induced Hyperprolactinemia Might Not Be that Stress-Induced as Argued: Observational Case-Control Study. Endocr Pract. Published 5 November 2024. doi:10. 1016/ j. eprac. 2024. 10. 013
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