Type 2 & other diabetes

Surgical ablation for atrial fibrillation: impact of Diabetes Mellitus type 2

Cardiovasc DiabetolPublished Observational cohort study

An erratum to this article was published (Cardiovasc Diabetol, 18 May 2023 ↗)

Authors' conclusion

Surgical ablation had a high success rate, with freedom from recurrent atrial arrhythmia at 1- 3- and 5- years follow-up in both the DM type 2 and non-DM groups. Furthermore,1- and 3-year mortality after surgical ablation was also similar in both groups. However, 5-year mortality was higher in the DM type 2 group.

Study context

Population
Patients who underwent surgical atrial fibrillation (AF) ablation (concomitant or isolated cardiac surgery), 2006–2021, Israel's largest tertiary care center
Participants
606 patients
Exposure
Diabetes mellitus (DM) type 2 vs non-diabetic patients undergoing surgical AF ablation
  • Non-DMn = 484reference
  • DM type 2n = 122
Outcome
Freedom from recurrent atrial arrhythmia and mortality
Methodological detailssingle-centre, tertiary care center
  • Single-centre
  • Tertiary care center

Main finding

As reported in the abstract

Freedom from AF · 1-year follow-up

P = 0.511

Observational data: associations, not effects.

Further findings

Freedom from AF · 3-year follow-up · similar

P = 0.290

Freedom from AF · 5-year follow-up · similar

P = 0.622

Mortality · 1 year · similar

P = 0.226

Mortality · 3 years · similar

P = 0.076

Mortality · 5 years · higher with DM type 2
P = 0.009
Baseline/operative characteristics — DM patients older, more hypertension and cerebrovascular accident (CVA)/transient ischemic attack (TIA), higher EuroSCORE · longer bypass time with DM type 2
P < 0.05 for all · P = 0.028

Mortality · 5 years

5-year mortality higher in DM type 2 vs non-DM

Original publication

Surgical ablation for atrial fibrillation: impact of Diabetes Mellitus type 2. Cardiovasc Diabetol. Published 31 March 2023. doi:10.1186/s12933-023-01810-x

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