Stable Iodine Intake and Thyroid Screening Outcomes After the Fukushima Nuclear Disaster: An Observational Study
Main finding · Screening results indicating need for detailed examinationResult — go to the resultOdds ratio 0.839 95% CI 0.393–1.8Authors' conclusion
Stable iodine intake was not associated with thyroid ultrasound screening results, probably because of the low radiation doses following the FDNPP accident. Parenchymal heterogeneity and thyroid volume were similar, supporting the conclusion that the adverse effects of single-dose stable iodine are minimal.
Study context
- Population
- Children born April 1998–March 2011 in Miharu Town, Fukushima, Japan, where stable iodine intake was implemented during the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident; regional thyroid screening program1,952 age- and sex-matched
- Participants
- 1,974 children
- Exposure
- Stable iodine intake vs no intake
- Intaken = 1,095
- Non-intaken = 879reference
- Outcome
- Thyroid ultrasound screening results indicating the need for a detailed examination
Methodological detailscoarsened exact matching for sex and age, logistic regression analysis
- Coarsened exact matching for sex and age
- Logistic regression analysis
Main finding
As reported in the abstract
Screening results indicating need for detailed examination
Odds ratio
0.839
95% CI 0.393–1.8
P = 0.647
Intakevs Non-intake
OR 0.839 (95% CI 0.393–1.8); P = 0.647
Observational data: associations, not effects.
Further findings
Thyroid volume and parenchymal heterogeneity
- Volume and parenchymal heterogeneity were not different between groups
Original publication
Stable Iodine Intake and Thyroid Screening Outcomes After the Fukushima Nuclear Disaster: An Observational Study. J Clin Endocrinol Metab. Published 29 May 2025. doi:10.
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