Osteoporosis, bone & mineral

The relationship between sarcopenia-related measurements and osteoporosis: The SARCOP study

Osteoporos IntPublished Cross-sectional study

Authors' conclusion

Loss of muscle mass/function (i.e., sarcopenia) can coexist with loss of trabecular and cortical bone. To this end, grip strength and anterior thigh MT seem to be associated with the lumbar vertebral BMD, while CST is associated with the femoral neck BMD. Lastly, low grip strength might have an association with postmenopausal OP.

Study context

Population
Community dwelling postmenopausal women from two physical and rehabilitation medicine outpatient clinics
Participants
546 participants
Outcome
Association of sarcopenia-related measurements (US anterior thigh muscle thickness, grip strength, chair stand test, gait speed) with lumbar/femoral BMD and presence of osteoporosis
Methodological detailsconsecutive inclusion, two outpatient clinics
  • Consecutive inclusion
  • Two outpatient clinics

Main finding

As reported in the abstract

Osteoporosis prevalence

Osteoporosis (T-score ≤ −2.5 SD at L1-L4 and/or femoral neck)

222

40.7%

Low grip strength (< 22 kg) increased risk of osteoporosis (OP) after adjustment for confounders

1.6 times

Observational data: associations, not effects.

Original publication

The relationship between sarcopenia-related measurements and osteoporosis: The SARCOP study. Osteoporos Int. Published 4 October 2022. doi:10.1007/s00198-022-06563-z

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