Risk factors for at-risk foot and peripheral artery disease among the population with diabetes: A multicommunity-based cross-sectional study
Authors' conclusion
The at-risk foot accounted for a high percentage among DM patients. Advanced age and renal dysfunction are independent risk factors for the at-risk foot. Glycemic control does not reduce the risk grade of at-risk foot and the incidence of PAD.
Study context
- Population
- Diabetes mellitus (DM) patients from the at-risk foot screening program of Shanghai, China, March 21–April 30, 2021
- Participants
- 3,030 patients
- Outcome
- Prevalence of at-risk foot
Methodological detailsmulticommunity-based
- Multicommunity-based
Main finding
As reported in the abstract
Prevalence of at-risk foot among DM patients
27.8%
Observational data: associations, not effects.
Further findings
Factors associated with higher at-risk grade (adjusted)
- Age, OR
- 1.04 (95% CI 1.02-1.06)
- Urinary albumin creatinine ratio, OR
- 1.001 (95% CI 1.000-1.002)
- Estimated glomerular filtration rate (eGFR), OR
- 0.991 (95% CI 0.984-0.998)
- HbA1c was not an independent risk factor for increased risk grade
- Adjusted
Peripheral artery disease (PAD)
- Incidence of PAD in all people with DM
- 11.1%
- Age, pulse rate and low-density lipoprotein were independent risk factors for PAD
- HDL, eGFR and lymphocyte-to-monocyte ratio were independent protective factors for PAD
- HbA1c was not an independent risk factor for more severe PAD
Original publication
Risk factors for at-risk foot and peripheral artery disease among the population with diabetes: A multicommunity-based cross-sectional study. Diabetes Res Clin Pract. Published 8 August 2023. doi:10.
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