Proposed bone health screening protocol to identify total knee arthroplasty patients for preoperative DXA
Authors' conclusion
A simple screening protocol identifies TKA patients with T-score and clinical osteoporosis for preoperative DXA with high sensitivity in this prospective cohort study.
Study context
- Population
- Elective primary TKA patients aged ≥ 50 years, all with routine clinical DXA68 females and 32 males
- Participants
- 100 patients
- Exposure
- Bone health screening protocol (sex, age, fracture history, FRAX) vs DXA-defined T-score and clinical osteoporosis
- Outcome
- Sensitivity and specificity of the screening protocol for osteoporosis (World Health Organization (WHO) T-score ≤ - 2.5, or clinical: T-score ≤ - 2.5, elevated BMD-adjusted FRAX risk, or prior hip/spine fracture)
Methodological detailsdiagnostic accuracy of a screening protocol
- Diagnostic accuracy of a screening protocol
Main finding
As reported in the abstract
Screening protocol for identifying T-score osteoporosis (WHO criteria, T-score ≤ −2.5)
Screening sensitivity
1.00
CI 0.79–1.00
Screening specificity
0.37
CI 0.27–0.48
Observational data: associations, not effects.
Further findings
Screening protocol for identifying clinical osteoporosis
- Screening sensitivity
- 1.00 (CI 0.92-1.00)
- Screening specificity
- 0.54 (CI 0.41-0.68)
- 43 patients with clinical osteoporosis
Original publication
Proposed bone health screening protocol to identify total knee arthroplasty patients for preoperative DXA. Osteoporos Int. Published 3 November 2022. doi:10.
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