Prevalence, trends, and determinants of early-onset type 2 diabetes in northwest China: a sex-stratified analysis of ∼10 million community-dwelling population
Authors' conclusion
This large population-based cohort study shows early-onset type 2 diabetes increased by 50% from 2019 to 2022 in northwest China. Obesity and low education emerged as the strongest modifiable risk factors, and male showed the highest overall risk.
Study context
- Population
- Community-dwelling adults aged 18–39 years, Northwest China Tianshan Cohort (2019–2023)of 9,641,234 retained
- Participants
- 4,130,431 adults
- Outcome
- Annual prevalence and trends of early-onset T2D, defined by objective indicators
- Follow-up
- 2019-2023
Methodological detailssex-stratified analysis, Cox proportional hazard regression
- Sex-stratified analysis
- Cox proportional hazard regression
Main finding
As reported in the abstract
Early-onset T2D prevalence · 2019 to 2022
Prevalence rose from 1.50% to a 2022 peak of 2.25%
1.50% to 2.25%
Observational data: associations, not effects.
Further findings
Risk factors for early-onset T2D
- Older age, male, lower education, civil servant, divorced/widowed, higher BMI and current smoker significantly associated with higher risk, most in a dose-dependent manner
- Associations largely consistent between sexes, with a few exceptions in BMI subgroups
Original publication
Prevalence, trends, and determinants of early-onset type 2 diabetes in northwest China: a sex-stratified analysis of ∼10 million community-dwelling population. Diabetes Res Clin Pract. Published 16 May 2026. doi:10.
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