Type 2 & other diabetes

Prevalence of SGLT2 inhibitor and GLP1 receptor agonist prescriptions in type 2 diabetes patients with and without chronic kidney disease: Analysis of an Australian primary care dataset

Diabetes Obes MetabPublished Retrospective cohort study

Authors' conclusion

We observed low rates of SGLT2 inhibitor and GLP1-RA prescriptions in patients with T2DM irrespective of CKD status. Strategies are needed to improve prescription rates, with a particular focus on patients with high kidney and cardiovascular risk.

Study context

Population
Adults with T2D attending Australian primary care practices participating in MedicineInsight36,840 (32.1%) with chronic kidney disease (CKD)
Participants
114,499 adults
Exposure
T2D patients with CKD vs without CKD
  • With CKDn = 36,840
Outcome
Percentage of patients with ≥1 prescription for an SGLT2 inhibitor or a GLP1-RA (assessed separately), CKD vs no CKD
Follow-up
2020-2021

Main finding

As reported in the abstract

≥1 SGLT2 inhibitor prescription

Observational data: associations, not effects.

Further findings

OutcomeWith CKDTrial target population
≥1 GLP1-RA prescription · 2020-2021Assessed separately; part of the outcome of interest10.1%11.3%
  • ≥1 GLP1-RA prescription: No CKD 8.8%

Factors associated with prescription

More advanced CKD stage and severely increased albuminuria were associated with a lower likelihood of SGLT2 inhibitor or GLP1-RA being prescribed

Original publication

Prevalence of SGLT2 inhibitor and GLP1 receptor agonist prescriptions in type 2 diabetes patients with and without chronic kidney disease: Analysis of an Australian primary care dataset. Diabetes Obes Metab. Published 16 July 2025. doi:10.1111/dom.16608

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