Prevalence, Safety, and Metabolic Control Among Danish Children and Adolescents with Type 1 Diabetes Using Open-Source Automated Insulin Delivery Systems
Authors' conclusion
This study is the first to provide knowledge on pediatric users of OS-AID systems in Denmark and found a prevalence of 1.89% for OS-AID systems, improved TIR, and no increased risk associated with use of OS-AID systems.
Study context
- Population
- Danish children and adolescents with T1D using open-source automated insulin delivery (OS-AID) systems, recruited via pediatric diabetes outpatient clinics and social media; median age 12 [IQR 11–14] years, 51% females56 users identified
- Participants
- 31 children
- Exposure
- Before vs during use of OS-AID systems
- Outcome
- Prevalence of OS-AID use among Danish children and adolescents with T1D
Methodological detailsMean duration of OS-AID use 2.37 ± 0.86 years
- Mean duration of OS-AID use 2.37 ± 0.86 years
Main finding
As reported in the abstract
Users of OS-AID systems identified out of 2950 children and adolescents with T1D
56
Prevalence of OS-AID systems
1.89%
Observational data: associations, not effects.
Further findings
TIR
- TIR increased from mean 62.29% ± 13.68% to 70.12% ± 10.08%
- *P < 0.01
HbA1c
- HbA1c decreased from mean 50.13 ± 5.76 mmol/mol (6.7% ± 2.7%) to 47.86 ± 6.24 mmol/mol (6.5% ± 2.7%)
- **P < 0.05
Parental sleep quality (Pittsburgh Sleep Quality Index)
- Parents reported better quality of sleep
Safety
- No changes were found in safety parameters
Original publication
Prevalence, Safety, and Metabolic Control Among Danish Children and Adolescents with Type 1 Diabetes Using Open-Source Automated Insulin Delivery Systems. Diabetes Technol Ther. Published 25 March 2024. doi:10.
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