Type 2 & other diabetes

Prescribing of evidence-based diabetes pharmacotherapy in patients with metabolic dysfunction-associated steatohepatitis

BMJ Open Diabetes Res CarePublished Cross-sectional study

Authors' conclusion

EBP prescriptions, especially pioglitazone, are low in patients with T2D and MASH, regardless of race/ethnicity. These data underscore the need for interventions to close the gap between current and evidence-based care.

Study context

Population
Patients with T2D and MASH (diagnosis codes, January 2019–January 2021) with ≥1 primary care or endocrinology encounter, Duke University Health System; mean age 59.7 (SD 12) years, 61.9% female
Participants
847 patients
Exposure
EBP prescribing across racial/ethnic groups
  • Blackn = 101
  • Latino/a/xn = 39
Outcome
EBP: ≥1 prescription for pioglitazone and/or a GLP-1RA during the study period
Methodological detailssingle health system
  • Single health system

Main finding

As reported in the abstract

EBP prescribed
Each group vs whiteAdjusted odds ratio (95% CI)P value
Latino/a/x
1.82(0.78–4.28)
Black
0.76(0.44–1.33)
P = 0.20
EBP prescribed, all patients
34.8% (n=295)

Observational data: associations, not effects.

Original publication

Prescribing of evidence-based diabetes pharmacotherapy in patients with metabolic dysfunction-associated steatohepatitis. BMJ Open Diabetes Res Care. Published 29 November 2023. doi:10.1136/bmjdrc-2023-003763

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