Type 2 & other diabetes

Prediabetes Prevalence by Adverse Social Determinants of Health in Adolescents

JAMA Netw OpenPublished Cross-sectional study

Authors' conclusion

Adverse SDOH were associated with higher prediabetes prevalence, across and within racial and ethnic categories. Consideration of adverse SDOH may offer a more actionable alternative to race- and ethnicity-based screening to evaluate T2D risk in youth.

Study context

Population
Youths aged 12 to 18 years with body mass index (BMI) ≥85th percentile without known diabetes, NHANES 2011–2018; mean age 15.5 years, 50.5% femalerepresenting 10,178,400 US youths
Participants
1,563 participants
Exposure
Adverse social determinants of health (SDOH) present vs absent
Outcome
Elevated hemoglobin A1c (HbA1c) ≥5.7% (prediabetes or undiagnosed presumed T2D)
Methodological detailssurvey-weighted logistic regression, adjusted for age, sex and BMI z score, Data from 2011 to 2018 NHANES cycles, analysed June 1, 2023, to April 5, 2024
  • Survey-weighted logistic regression
  • Adjusted for age, sex and BMI z score
  • Data from 2011 to 2018 NHANES cycles, analysed June 1, 2023, to April 5, 2024

Main finding

As reported in the abstract

Prediabetes prevalence associated with each adverse SDOH (adjusted for race, ethnicity and BMI z score)

Food insecurity independently associated with higher prediabetes prevalence

4.1%

95% CI 0.7%–7.5%

Public insurance independently associated with higher prediabetes prevalence

5.3%

95% CI 1.6%–9.1%

Low income independently associated with higher prediabetes prevalence

5.7%

95% CI 3.0%–8.3%

Observational data: associations, not effects.

Further findings

Prediabetes prevalence by number of adverse SDOH among White youths
Percent
3 adverse SDOH
8.3%(CI 4.9%–11.8%)
0 adverse SDOH
0.6%(CI −0.7%–2.0%)

Prediabetes prevalence by race and ethnicity

Asian, Black and Hispanic youths had higher prediabetes prevalence overall

Original publication

Prediabetes Prevalence by Adverse Social Determinants of Health in Adolescents. JAMA Netw Open. Published 3 June 2024. doi:10.1001/jamanetworkopen.2024.16088

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