Pituitary & hypothalamus

Point‐of‐care ultrasound is a useful adjunct tool to a clinician's assessment in the evaluation of severe hyponatraemia

Clin Endocrinol (Oxf)Published Diagnostic accuracy study

Authors' conclusion

As subjective clinical and biochemistry assessments of fluid status are often unreliable due to co-morbidities and concurrent use of medications, POCUS can be a rapid objective diagnostic tool to assess fluid status in patients with severe hyponatraemia, to guide accurate emergency fluid management.

Study context

Population
Patients with severe hyponatraemia (serum Na <120 mmol/L) managed by standard care
Participants
19 patients
Comparison
Point-of-care ultrasound (POCUS) vs clinician assessment of fluid status, against final diagnosis at discharge
Outcome
Agreement of fluid status assessment (hypovolaemia, hypervolaemia or euvolaemia) with final diagnosis at discharge by retrospective case review

Performance

As reported in the abstract

Agreement with final diagnosis of fluid status

P = 0.1611

Further findings

Serum Na · admission

Median Na on admission (mmol/L)
113 (109-116)
Na on discharge (mmol/L)
129 ± 3

Unreliable biochemistry

Biochemistry unreliable, likely due to renal failure, polypharmacy or diuretic use
58% (n = 11/19)

Thirst and hypovolaemia

Thirst symptom correlated to hypovolaemia
80% (4/5)

Safety

Inappropriate emergency fluid management based on initial clinician assessment

Inappropriate emergency fluid management
37% (n = 7/19)

Original publication

Point‐of‐care ultrasound is a useful adjunct tool to a clinician's assessment in the evaluation of severe hyponatraemia. Clin Endocrinol (Oxf). Published 16 January 2024. doi:10.1111/cen.15024

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